How about Di-Creatine Malate with Orotic Acid. I asked a Shawn Well of Man Sports about a good creatine, and his thoughts on Arginine, this is what he replied...
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Arginine: Clinical potential of a semi-essential amino.
Appleton J.
Department chair, National College of Naturopathic Medicine, Portland, OR 97201, USA.
[email protected]
Arginine, a semi-essential amino acid, is involved in numerous areas of human biochemistry, including ammonia detoxification, hormone secretion, and immune modulation. Arginine is also well known as a precursor to nitric oxide (NO), a key component of endothelial-derived relaxing factor, an endogenous messenger molecule involved in a variety of endothelium-dependent physiological effects in the cardiovascular system. Because of arginine's NO-stimulating effects, it can be utilized in therapeutic regimens for angina pectoris, congestive heart failure, hypertension, coronary heart disease, preeclampsia, intermittent claudication, and erectile dysfunction. In addition, arginine has been studied in the treatment of HIV/AIDS, athletic performance, burns and trauma, cancer, diabetes and syndrome X, gastrointestinal diseases, male and female infertility, interstitial cystitis, immunomodulation, and senile dementia. Toxicity, dosage considerations, and contraindications are also reviewed.
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On the wikipedia you'll see the EAA and ariginie is an EAA in growth, development and trauma situations...guess what bodybuilding is? It may not be essential to many, but certainly it is in this case!
Ethyl Ester is garbage hype, the science is poor at best on CEE and the extrapolation to aminos is laughable. Bodybuilding hype and VPX and nutrabolics are pioneering the way towards garbage...will they still work...yes...any better...no...health risks...maybe...higher cost...yup.
Malate makes sense as a krebs cycle intermediate. Pyroglutamte is the form used with Lysine to ellicit GH release. And you'd better use lysine with whopping doses of arginine as it can trigger herpes outbreak (many people have simplex...cold sores). The best form in mind is AAKG removing ammonia and anticatabolic effects. The Diarginine form is interesting because dipeptides absorb faster than free form...this would apply to both AAKG and Diarginine Malate. NO products are overhyped, pumps does not equal mass...as creatine quite frankly is overhyped as pump/swole looking muscles are equated with mass as is water weight. Not saying both don't have their place, but certainly not more important than macronutrient timing or electrolytes/hydration as discussed in the thread. BTW for creatine the Tri-cretaine Orotate or Kre-Alkalyn are solid. CM is good to, but water weight and GI distress knock it down.