Lysine VS Arginine

[Pleonastic]

I've been taking Lysine since December 1500mg a day. I read it suppresses arginine, which is converted to nitrogen by the body. So is this hurting my muscle building a lot, a little or not at all?

 

[PublicEnemy]

I've been taking Lysine since December 1500mg a day. I read it suppresses arginine, which is converted to nitrogen by the body. So is this hurting my muscle building a lot, a little or not at all?

Arginine is one of the cofactors involved in the synthesis of Nitric Oxide, but it is not converted into nitrogen in the body. By definition, all amino acids contain nitrogen... Amino group =NH2 (primary amine).

And i doubt 1500mg of Lysine will inhibit any muscle growth. For what reasons are you supplementing with it?

 

[xjsynx]

I wouldn't sweat it, in fact most people are deficient in Lysine.

When do you dose the Lysine? Post-workout is very ideal.

 

[nemo]

From what I've heard , arginine effects the uptake of lysine, not the other way around.
I'm no expert though!

 

[PublicEnemy]

From what I've heard , arginine effects the uptake of lysine, not the other way around.
I'm no expert though!

I think they're competitive but don't quote me on it. Besides histidine, they are the only other two amino acids that are basic.

I just know Lysine works magic on cold sores... Whenever I feel an outbreak coming I'll start taking in about 3-4 grams a day and it usually cuts the life of the sore down by 2-3 days. For me, at least, it will usually decrease the size too, makes them much less noticeable.

 

[Pleonastic]

Arginine is one of the cofactors involved in the synthesis of Nitric Oxide, but it is not converted into nitrogen in the body. By definition, all amino acids contain nitrogen... Amino group =NH2 (primary amine).

And i doubt 1500mg of Lysine will inhibit any muscle growth. For what reasons are you supplementing with it?

Had a bad cold sore in December, I know theres no cure but these are said to lessen them.

 

[Pleonastic]

I wouldn't sweat it, in fact most people are deficient in Lysine.

When do you dose the Lysine? Post-workout is very ideal.

Pretty random in my doses, normally in the late morning like 10AM. I haven't done it post workout. I will try though.

 

[PublicEnemy]

Had a bad cold sore in December, I know theres no cure but these are said to lessen them.

I haven't seen any clinical studies on Lysine's effect on cold sores but I did read somewhere that it competitively inhibits one of the enzymes involved in a cold sore outbreak once the virus attacks, which will limit the increase of virus formation. I also know that high arginine levels are thought to increase the risk of an outbreak, that's why on the majority of arginine based NO products they say not to take if you have a history of cold sore outbreaks.

 

[Jessep76]

The dose should be around 1875mg-2500 when an outbreak is coming on. 1250mg for prevention. No more than 3000mg.
Andrographis and Olive leaf is also good and non toxic. Vitamin C boosts the andrographis.

 

[Pleonastic]

I haven't seen any clinical studies on Lysine's effect on cold sores but I did read somewhere that it competitively inhibits one of the enzymes involved in a cold sore outbreak once the virus attacks, which will limit the increase of virus formation. I also know that high arginine levels are thought to increase the risk of an outbreak, that's why on the majority of arginine based NO products they say not to take if you have a history of cold sore outbreaks.

I have read all the same stuff, thats why I take it. But I have never seen any of the warnings on the NO high arginine products about cold sores.

 

[Dyou]

i read arginine does lower your lysine absorbtion, which makes me think thats the reason it will cause a cold sore. and also some say not having enough b12 "Medical research in England found that many people with cold sores were low in B12, and that by adding 250 mcg. of B12 the condition improved rapidly. This research also suggested taking B complex supplements with emphasis on the B12 and folic acid"

"Researchers have found that the ratio of the amino acids arginine and lysine plays an important part in controlling (not curing!) cold sores. Arginine aids the growth and reproduction of the herpes virus, while lysine inhibits it. Foods containing chocolate, peanuts and other nuts, grains, peas, seeds, oatmeal and whole-wheat products should be cut out or reduced from the diet. These foods are high in arginine"

2 random articals i have read

 

[ShiftyCapone]

While I've never personally had a cold sore before (I have no personal experience or factual evidednce), but I have friends who absolutely swear by lysine supplementation to reduce the longevity of an outbreak. Seems to be relatively effective from what I have seen of them...

that's why on the majority of arginine based NO products they say not to take if you have a history of cold sore outbreaks.

I've never heard that before.... Interesting nonetheless.

 

[Funny Monkey]

Yeah Public Enemy is right Arginine can promote cold sore breakouts.
Whenever I feel a cold sore coming on I take about 3 grams a day of Lysene it will still break out but very little and it only lasts about 4 days as opposed to 9 or so. I love the stuff!

 

[Nootropix]

I wonder if creatine can promote cold sore break outs because it's made up of arginine, glycine, and methionine.

 

[Savantee]

Creatine & Herpes I/II

I wonder if creatine can promote cold sore break outs because it's made up of arginine, glycine, and methionine.

Nootropics, Just the opposite in fact creatine supplementation is actually very beneficial to those who suffer from Herpes I/II.

I think pubmed has an article that states as much :

Does supplemental creatine prevent herpes recurrences?
Ness SR, McCarty MF.

Pantox Laboratories, San Diego, California 92109, USA.

While functioning as a general practitioner at the Camp Pendleton Marine Base, the first author treated numerous patients with recurrent genital herpes. Beginning in 1998, a number of these patients failed to return for periodic acyclovir therapy. Inquiries revealed that these patients had all commenced supplemental creatine after their last outbreak, and had experienced no further outbreaks. A literature search uncovered a report that cyclocreatine, a synthetic compound structurally and functionally homologous to creatine, inhibits the replication of cytomegalovirus, varicella-zoster, and herpes simplex types 1 and 2, in low millimolar concentrations; furthermore, dietary cyclocreatine reduces morbidity and mortality in mice infected with HSV-2. The fact that both creatine and cyclocreatine exert neuroprotective and cancer-retardant effects in rodents, encourages the speculation that creatine shares the anti-viral activity of cyclocreatine. Pilot studies to assess the impact of creatine loading on recurrence of oral and genital herpes appear warranted; the impact of creatine on shingles occurrence in high-risk patients could also be explored. Although initially conceived as an aid to athletic performance, creatine loading may prove to have broad preventive and therapeutic applications.


There are many people who have successfully sorted themselves out with a long cycle to saturate system and then large doses to firefight outbreaks...