Lowat? New fat lost product

Ev52

Well-known member
Anybody else investigated this? Any companies planning on using it?

LOWAT™ is a patent-pending weight management ingredient consisting of Piper betle leaf and Dolichos biflorus seed extracts that has been clinically shown to promote weight loss. These natural extracts uniquely combine to target fat. Clinical research has shown that LOWAT™ significantly increases serum adiponectin concentration, indicating a possible reduction in fat stores. Adiponectin, a hormone produced and secreted by fat cells, regulates the breakdown of fat. Preliminary research suggests that LOWAT™ inhibits adipogenesis (generation and accumulation of fat in the fat cells) and increases lipolysis (breakdown of stored fat) in mature fat cells. LOWAT™ has been shown in randomized, double-blind, placebo-controlled research to significantly reduce body weight 2.4x better than placebo after eight weeks. While weight loss was already evident two weeks into the study, significant weight loss of around 9 lbs was seen at week eight.
 
LOWAT™ works by targeting fat. Clinical research shows that LOWAT™ increases the fat-burning hormone adiponectin, indicating increased fat metabolism leading to a decrease in body fat percentage. Preliminary research shows that LOWAT™ increases lipolysis and decreases adipogenesis thereby reducing fat accumulation and formation. Clinical research also shows that LOWAT™ decreases the hunger-inducing hormone, ghrelin, indicating a satiety-promoting benefit
 
It's made by interhealth usa. There has only been this study that I can find.

Creighton University School of Medicine researcher, Archana Chatterjee, MD, PhD, presented clinical research findings on InterHealth Nutraceutical’s new weight management ingredient, LOWAT, at the 51st American College of Nutrition Meeting in New York City, October 7-9.

In a randomized, double-blind, placebo-controlled, eight-week study, 50 human subjects took 900 mg a day (300 mg 3x/day, 30 minutes before meals) of LOWAT™ or a placebo. All subjects followed a 2,000 calorie daily diet and walked for 30 minutes five days a week.

Results showed that LOWAT:

* Significantly decreased body weight 2.4x better than placebo at 8 weeks (p<0.00005) - 9.4 lbs compared to 3.9 lbs
* Reduced body weight as early as 2 weeks - 3.1 lbs compared to 1.7 lbs
* Significantly reduced BMI 2.4x better than placebo at 8 weeks (p<0.00005) - 1.66 kg/m2 compared to 0.71 kg/m2
* Reduced BMI as early as 2 weekss - 0.54 kg/m2 compared to 0.31 kg/m2

The supplemented group also showed a 15% increase in serum adiponectin concentration compared to placebo (p<0.05). This observation suggests a possible reduction in fat stores in supplemented subjects since adiponectin promotes the burning of fat for energy, maintains a high metabolic rate and is inversely correlated with body fat percentage. The supplemented group also showed a 17% reduction in serum levels of the hunger-inducing hormone ghrelin compared to placebo (p<0.05). Better reduction in serum glucose and triglycerides was observed in the supplemented group compared to placebo.
 
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