I have tried them ran about Three bottles, not back to back tho. I have to agree appetite suppression was very good had to remind myself to eat. They did change the formulas from the original unfortunately but still works good. even with new formula id say 1 a day max very early, if u want to do two I'd wait till after 15/20 days till u have a feeling of how it will work otherwise u won't get any sleep. First try should see 8_10 lbs lost.