Isoflavones and DHT

NeoNewfie

New member
Hi there,
I'm a total hack when it comes to this stuff, but I have a question regarding soy isoflavones.

I understand that they lower serum DHT through inhibition of the 5a-reductase enzyme, but I understand that they also inhibit 3a-HSD. Wouldn't the latter lead to more DHT through the inhibition of its breakdown into 5a-androstane-3a,17b-diol? I ask b/c I wonder if the DHT-raising effects of creatine or green tea might be rendered more anabolic through the suppression of 3a-HSD through the intake of soy isoflavones.

Can anyone set me straight?
 
Sounds like your coming onto something. Would like to know also! Hopefully insight linked with reputable sources and no "bro science".
 
Indomethican, a prescription anti-inflammatory, apparently suppresses 3a-HSD, but I don't want to mess with that.
 
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