Why do you want to take a break? TRT is for life. There is no need to take a break if you are running labs routinely and results are good. Even then, the things that can get out of line (most of the time) are controllable relatively easily (E, E2). If your PSA is elevated or your RBC goes up, you may have to back off, but that is between you and your physician.
My opinion based on my personal experience.