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Is DMT Reduced by 5-AR?

Mass_69 said:
Yes.

17a-methyl-5a-androst-2-ene-17b-ol
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i believe he asked if DMT is reduced in the body by 5AR. the answer is NO, DMT is already 5A-reduced, which is mostly what accounts for the androgenic sides (libido, acne, strength, hairloss, etc)
 
same_old said:
i believe he asked if DMT is reduced in the body by 5AR. the answer is NO, DMT is already 5A-reduced, which is mostly what accounts for the androgenic sides (libido, acne, strength, hairloss, etc)
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Thanks. But I thought being 5-alpha reduced doesn't necessarily mean it's a strong androgen receptor agonizer. Like Deca is reduced to a weaker compound, while non-reduced Deca is the stronger androgen.
 
SubliminalX said:
Thanks. But I thought being 5-alpha reduced doesn't necessarily mean it's a strong androgen receptor agonizer. Like Deca is reduced to a weaker compound, while non-reduced Deca is the stronger androgen.
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DHN is the exception, not the rule. virtually all 5A-reduced steroids are dry (of course), hardening, good for strength, unfriendly to those with MPB or BPH...and many cause acne and aggression to a greater degree than their unconverted counterparts.
 
SubliminalX said:
Thanks. But I thought being 5-alpha reduced doesn't necessarily mean it's a strong androgen receptor agonizer. Like Deca is reduced to a weaker compound, while non-reduced Deca is the stronger androgen.
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oh and a compound's androgenicity and its AR affinity are not the same thing...although they can feasibly be related, as androgenic sides will be exhibited more on a stronger steroid.
 
same_old said:
i believe he asked if DMT is reduced in the body by 5AR. the answer is NO, DMT is already 5A-reduced
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Actually, the question simply said, "Is DMT Reduced by 5-AR?" and the answer is yes, it IS reduced by 5a-reductase in it's current state (as you yourself went on to say). Maybe the question should have asked, "Is DMT Reduced/Effected in the Body by 5a-Reductase?"


Smart-A$$...
 
Mass_69 said:
Actually, the question simply said, "Is DMT Reduced by 5-AR?" and the answer is yes, it IS reduced by 5a-reductase in it's current state (as you yourself went on to say). Maybe the question should have asked, "Is DMT Reduced/Effected in the Body by 5a-Reductase?"

Smart-A$$...
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i dont believe DMT ever encounters the 5A reductase enzyme during its pharmaceutical manufacture...therefore the answer is still "no."

anyway, this is all semantics. i think we have made it clear what the actual scenario is.
 
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