Introducing TruCDP

Synapsin

Synapsin

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PEScience TruCDP

Introducing the newest addition to PEScience’s essentials line, TruCDP. CDP-choline (also known as citicoline) is a molecule that raises levels of choline and uridine in the body (1).

CDP-choline is created through the enzymatic breakdown of orotic acid and choline chloride by C. ammoniagenes and E. coli. Orotic acid is found in the milk of cows and is DSHEA approved. Choline chloride is also DSHEA approved (1). It belongs to a group of molecules known as nucleotides (1). CDP-choline has obtained novel food registration status in Europe (2), and has gained generally recognized as safe (GRAS) status (3). CDP-choline is a water-soluble compound, and it is extremely bioavailable (over 90% bioavailable) (4).

A study in healthy middle-aged humans showed that a 250 mg dose of CDP-choline over the course of 28 days improved attention and cognitive performance (5).

Another study in healthy adolescent humans done over the course of 28 days showed that 250 mg of CDP-choline improved attention and cognitive performance (6); the importance of this finding is that it shows that CDP-choline improves attention and cognitive performance in humans across age groups.

References

1. Safety Assessment of Citicoline. Retrieved from: https://www.fsai.ie/uploadedFiles/Science_and_Health/Novel_Foods/Applications/2012 Citicholine.pdf

2. Kyowa Hakko’s Citicoline obtains Novel Food Registration status in Europe. Retrieved from:
Kyowa Hakko?s Citicoline obtains Novel Food Registration status in Europe - Cognizin

3. Kyowa Hakko affirms GRAS for citicoline. Retrieved from: Kyowa Hakko affirms GRAS for citicoline

4. Secades, J. (2011). Citicoline: pharmalogical and clinical review, 2010 update. Revista de Neurologia. 52:2.

5. McGlade, E., Locatelli, A., Hardy, J., et al. (2012). Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women. Food and Nutrition Sciences. 3: 769-773.

6. McGlade, E., Agoston, A., DiMuzo, J., et al. (2015). The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males. Journal of Attention Disorders. July 15, 2015. 1-14.
 
jgntyce

jgntyce

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A great stale supp from a great company!
 
Driven2lift

Driven2lift

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Thank you for writing this up good sir
 

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