How good is Liv-52?

locutus24

locutus24

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When on a cycle I sometimes add in a little dianabol or superdrol with the injectables to get extra gains and a guy recommended Liv-52 for protection from liver damage. Wanted to know if any one used Liv 52 with good success, meaning that their liver health remained good or mostly good throughout a cycle using methylated compounds?

I saw a peer-reviewed article that said it was effective in treating liver cirrhosis patients.


At end they say:

"We conclude that Liv-52 possess hepatoprotective effect in cirrhotic patients. This protective effect of Liv-52 can be attributed to the diuretic, anti-inflammatory, anti-oxidative, and immunomodulating properties of the component herbs."
 
tyga tyga

tyga tyga

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When NAC and TUDCA are so readily available idk why you would get anything else.
 
locutus24

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Normally get UDCA (not TUDCA), the stuff they use in hosptials for people with liver cirrhosis, from a sarm company in Canada, but they are out of stock so looked at Liv-52 and other alternatives. I'll look into TUDCA!
 
StarScream66

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Liv-52 is pretty old school. It's just a combination of milk thistle and other herbs that protect the liver. I don't know a thing about TUDCA, but just plain NAC works fine. We've found (as a bodybuilding community) better stuff that Liv-52, I think that's pretty much the general assumption.
 
rubberring

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TUDCA and polyunsaturated phosphatidylcholine (PPC) are the two best things out there for liver protection while cycling orals. Both were the main ingredients in Anteus Labs' 'Aegis' product. You can still get PPC from Life Extension's 'Hepatopro'. Recommended dosage is 1800mg daily. I also use NAC year-round for its OCD benefits.
 
Renew1

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TUDCA and polyunsaturated phosphatidylcholine (PPC) are the two best things out there for liver protection while cycling orals. Both were the main ingredients in Anteus Labs' 'Aegis' product. You can still get PPC from Life Extension's 'Hepatopro'. Recommended dosage is 1800mg daily. I also use NAC year-round for its OCD benefits.
Aegis was top of the line.
 
MP3

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If you're running methylated prohormones or anabolic steroids you need Tudca. NAC is a nice add on. Milk thistle is give or take. Liv52, add it sure but you still need Tudca. As someone who visits a liver specialist, milk thistle and nac itself wont do ****
 
tyga tyga

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locutus24

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NAC sounds
If you're running methylated prohormones or anabolic steroids you need Tudca. NAC is a nice add on. Milk thistle is give or take. Liv52, add it sure but you still need Tudca. As someone who visits a liver specialist, milk thistle and nac itself wont do ****
UDCA is what I normally use and It works great and my liver health was monitored and levels stayed good. Just hard to find another place that sells legit stuff right now. Was getting it for 2 years until out of stock as more customers started buying it. I have heard of TUDCA in the past but never used it and barely glanced at it until now. It looks okayish as an alternative to UDCA as it has been used by other hospitals in countries besides USA for liver disease (not approved by FDA) so probably will get TUDCA (and maybe NAC) instead for time being. Question resolved!
 
rubberring

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UDCA is what I normally use and It works great and my liver health was monitored and levels stayed good. Just hard to find another place that sells legit stuff right now. Was getting it for 2 years until out of stock as more customers started buying it. I have heard of TUDCA in the past but never used it and barely glanced at it until now. It looks okayish as an alternative to UDCA as it has been used by other hospitals in countries besides USA for liver disease (not approved by FDA) so probably will get TUDCA (and maybe NAC) instead for time being. Question resolved!
TUDCA is just the taurine conjugate form of UDCA, and actually worked better in some pubmed liver studies iirc, so you should see the same results you saw with UDCA.
 
Mathb33

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TUDCA is just the taurine conjugate form of UDCA, and actually worked better in some pubmed liver studies iirc, so you should see the same results you saw with UDCA.
Then why is UDCA the first thing they usually give as prescription or in the hospital if you’re in a critical situation?
 
locutus24

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TUDCA and polyunsaturated phosphatidylcholine (PPC) are the two best things out there for liver protection while cycling orals. Both were the main ingredients in Anteus Labs' 'Aegis' product. You can still get PPC from Life Extension's 'Hepatopro'. Recommended dosage is 1800mg daily. I also use NAC year-round for its OCD benefits.
I don't know much about PPC and will research it, but what is your recommended dosage of TUDCA when taking superdrol at 10mg/day for 2-3 weeks?
 
rubberring

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Then why is UDCA the first thing they usually give as prescription or in the hospital if you’re in a critical situation?
Not sure, but here's one study...

https://pubmed.ncbi.nlm.nih.gov/7615206/
"Conclusions: Low doses of TUDCA and UDCA protect Hep G2 cells from EtOH-induced cytotoxicity. However, TUDCA seems to be more effective than UDCA in reversing the damage."

I don't think there's much of a difference between the two when it comes to proactively protecting the liver on cycle.

EDIT: Unlike UDCA, TUDCA is not FDA approved for medical use. Since they're practically the same and both created synthetically for cheap, there's no point in spending money on studies to prove TUDCA's safety profile. My $0.02
 
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rubberring

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I don't know much about PPC and will research it, but what is your recommended dosage of TUDCA when taking superdrol at 10mg/day for 2-3 weeks?
I would take 500-750mg daily for "proactive" protection. However, even lower doses have been excellent for improvement of bile salt composition and overall liver repair (reactive).

From Examine.com:

"10-13mg daily has once been shown to improve liver regenesis rates in a clinically ill population, and may be the lowest estimate of an active oral dose. When looking at improving bile salt composition, a dose around 15-20mg/kg bodyweight TUDCA seems best according to one study."

Btw, I think the way you're using Superdrol is really smart. I've learned that 2-3 weeks with harsh orals is the way to go when taking injectables. Nothing but fatigue and toxicity after week 3 for me. I do the same with M-Sten.
 
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rubberring

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Just a side note... I would not take TUDCA daily for months. Prolonged use can cause a worsening of pre-existing psoriasis and cause other rashes/very dry skin. It's meant for short-term protection and for repair. Also, SelfHacked.com has a nice page on TUDCA.
 
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StarScream66

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Then why is UDCA the first thing they usually give as prescription or in the hospital if you’re in a critical situation?
I couldn't find any evidence UDCA is administered for life threatening situations in the ER for a critical liver failure (Admittedly, I didn't look very far, so if you could link to an article/study, I will check it out). However, NAC is well known to be used in the ER for people who have overdosed on Tylenol because it's liver regeneration properties are so potent.

 
Mathb33

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I couldn't find any evidence UDCA is administered for life threatening situations in the ER for a critical liver failure (Admittedly, I didn't look very far, so if you could link to an article/study, I will check it out). However, NAC is well known to be used in the ER for people who have overdosed on Tylenol because it's liver regeneration properties are so potent.

At work right now, Don’t know if you’re used to the website ncbi for studies but you’ll see a lot about it. Basically UDCA is the only approved drug in the US in that regard. I’m also speaking of anecdotal evidence since this is what they gave me when my liver was 5 times out of range and also what they prescribed my friend when he was in early stage of liver cirrhosis.
 

bigdadybry

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I am curious as to why, with such a regenerative organ like the liver, there is such a strong "need" to protect it?
It is the Rocky Balboa of the body... punch drunk, slurred speech, unintelligent, but takes a beating and gets up for more.

Not trying to start a thread war, battle of the brains and research studies, and I am not advocating for the neglect of the liver.

I am seriously curious if anyone has had any serious liver issues aside from temporarily elevated enzymes? Issues which would serve to contraindicate the use of hepatotoxic drugs without concurrent administration of a liver protectant.
 
Mathb33

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I am curious as to why, with such a regenerative organ like the liver, there is such a strong "need" to protect it?
It is the Rocky Balboa of the body... punch drunk, slurred speech, unintelligent, but takes a beating and gets up for more.

Not trying to start a thread war, battle of the brains and research studies, and I am not advocating for the neglect of the liver.

I am seriously curious if anyone has had any serious liver issues aside from temporarily elevated enzymes? Issues which would serve to contraindicate the use of hepatotoxic drugs without concurrent administration of a liver protectant.
Depends who you talk to. I am much much more cautious about my heart than I am about my liver. Same for the kidneys.
 
StarScream66

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Your liver can regenerate, but when you are putting massive doses of hepatoxic drugs into your system it can overwhelm your liver and cause problems down the line.
 
Renew1

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Don’t feel so attacked old man I know you’re a very smart guy :)

Thanks bro.
Some days I feel like it. Today I'm just tired. Been getting ready for this Hurricaine.

... It's looking a little more promising, though.

:)
 
locutus24

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I would take 500-750mg daily for "proactive" protection. However, even lower doses have been excellent for improvement of bile salt composition and overall liver repair (reactive).

From Examine.com:

"10-13mg daily has once been shown to improve liver regenesis rates in a clinically ill population, and may be the lowest estimate of an active oral dose. When looking at improving bile salt composition, a dose around 15-20mg/kg bodyweight TUDCA seems best according to one study."

Btw, I think the way you're using Superdrol is really smart. I've learned that 2-3 weeks with harsh orals is the way to go when taking injectables. Nothing but fatigue and toxicity after week 3 for me. I do the same with M-Sten.
I appreciate the detailed info and you seem to know what you are talking about. I researched different brands of TUDCA and will be getting enough for at least 500 mg a day for about 5 weeks, as I am thinking I should take it a couple weeks after I stop use of sdol and also getting two liver check ups before use and after. How long do you use TUDCA after you finish using a methyl oral? You mentioned not taking it for too long in the second post after this one.

Yes, superdrol gives me good gains for small dosages and short periods of use. During use, usually after a couple days, I often will feel like I am about to get sick, but not actually sick; like the symptoms you get right before feeling the full symptoms of a cold/fever or flu, such as a vague feeling of nausea or tiredness. I hate the ambiguity of it during usage, but the gains are great! Always saying in my mind with sdol that "I should not take this too much longer or any more per day or else I might be seeing doctor or an ambulance soon."

M-sten is one of those designer steroids that is marketed as a PH right? I am curious about the ones still available that actually work (since they are actually steroids). Only currently marketed designer steroid I have taken was Max-LMG and got soggy/watery gains and less lean gains, even with daily AI and a smaller amount of test than usual to be sure if it was actually contributing anything to cycle. Maybe 2-3 lbs and I would say at most 1.5-2 lbs of lean gains or even 1. Actually I have no friggin idea if it worked. I guess it kind of sucked!
 
rubberring

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I appreciate the detailed info and you seem to know what you are talking about. I researched different brands of TUDCA and will be getting enough for at least 500 mg a day for about 5 weeks, as I am thinking I should take it a couple weeks after I stop use of sdol and also getting two liver check ups before use and after. How long do you use TUDCA after you finish using a methyl oral? You mentioned not taking it for too long in the second post after this one.
Your plan of using it a few weeks after stopping is solid imo. I'm not even sure how long or at what dose one would have to take TUDCA before experiencing major skin issues. I noticed my skin got really dry (especially scalp and feet) when I used it for 12 weeks. (I frontloaded a Test E cycle with M-Sten and finished with 6 weeks of Anavar, so I just kept the TUDCA throughout the entire cycle and a few weeks afterward.) I've only read about the psoriasis, as that's not an issue for me.

M-sten is one of those designer steroids that is marketed as a PH right? I am curious about the ones still available that actually work (since they are actually steroids).
M-Sten is apparently very similar in structure to Superdrol, as I seem to remember threads here about one converting to the other (?) Like Superdrol, it works quickly. The second and third weeks are a little mind-blowing, especially on a recomp. I've only gone as high as 20mg, but have gotten great results with as little as 8mg (OG 'Ultradrol'). Unlike the LMG, it's very dry and brings out the vascularity for me. Btw, the M-Sten from PRE is legit.

EDIT: I guess there were issues with M-Sten being "contaminated" with S-drol at some point... not "converting".
 
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rubberring

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Too often, my friend.
They rarely hit hard exactly where you are, but you have to prep for them anyway.
I can relate, bro. Grew up in Mobile, AL. The city took a direct hit from Hurricane Frederic when I was in the first grade. Now that I've been in northern California for the last 27 years, it's all about earthquake preparedness (or lack thereof, in my case).
 

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