I ran a six week, 3x a week pulse not too long ago of mdrol. calf and back pumps. More calf though for me, whenever i ran they felt SO tight. Also with my experiance i did fine on 20mg, but when i went to 30mg for one week i had extreme lethargy, i had GREAT gain with it though, helped my biceps start growing again FINALLY. I also would lose my appetite very easy at the end of the cycle and thats really weird for me. Also after cycle i lost a good portion of my libido, that was ****ty. But im fine now. If you can deal with the sides it's a great product as long as you take your supps.