Interesting stuff. How would one monitor prostate function via a metabolic panel lab? Maybe look at gfr or the other kidney labs since an inflamed prostate would affect kidney function?
I think most of you have read the recent studies on PSA and that the National Cancer Institute has found that a PSA level isn't such a good predictor of prostate cancer and can lead to many unnecessary biopsies. Many conditions can affect a PSA level, and many with a low PSA still develop cancer. I do not pay much attention to my PSA, which was 5.7 two weeks ago. Yesterday my doctor suggested getting a biopsy for peace of mind, I explained my position and he agreed. By the way, I get my blood panel done by LabCorp on my own, so by the time I see the doctor, I already have results... What I check for prostrate health are the eGFR, Serum Creatine, BUN, Calcium, Potassium, iron and DHEA. All of those affect kidney functions and if the kidney is showing signs of stress, then the prostrate will follow.
Let me get back to the blood panel and precautions ins a second. The medical community says that as we age, testosterone levels go down, DHT goes up and E2 goes up. I have not seen any rationale as to how DHT can go up if your test goes down, since DHT is a by product of test. I fully understand how E2 levels go up, by I'm not really convinced that DHT levels go up. What I think happens is that receptors may be more sensitive to DHT as our test levels go down, but I do not believe that DHT levels actually go up. But I cannot prove my point; it's only an opinion.
After my bout with prostatitis, I went from a TRT dose of 400/500 down to 200mgs per week. Within a month my test levels were within range, but my DHT was 131; the range is 30-85. My E2 was 18. So for some reason even with a normal level of test, my DHT is high, which on the surface supports the theory that as we age, DHT goes up for some reason. Still, that doesn't make sense since DHT is dependent upon the amount of test, so there has to be a ratio of test to DHT. Unless that ratio goes up as we age, I don't quite understand why my DHT didn't go down proportionately unless DHT stays in the blood much longer than test and therefore has a longer life, which I think is the case, so my DHT was still high from the anadrol and tren. But I'm merely speculating.
If you take any of the DHT blockers like Proscar, you're blocking all DHT activity, much like aromasen does estrogen, which cancels out the benefits of taking test to begin with. So I take Flomax,Tamsulosin, which binds to special proteins called alpha-1a adrenoceptors, which control signaling between the nervous system and the smooth muscle cells in the urinary system. When tamsulosin binds to these receptors, it blocks them, which keeps them from sending signals to tighten the smooth muscle. Tamsulosin is a selective alpha-blocker, sort of a SERM for the prostrate.
I need to do more experiments because quite frankly, my life depends on it. I'm going to blast a little starting next week, going from 200mgs of test to 400mgs per wk and ad 25mg of anadrol per day. Nothing too crazy, but significant. I am going to use aromasen EOD. Why, you may ask? Well, there seems to be an increase in DHT binding, even levels, when E2 goes up. So if I can control my DHT to the prostrate while blasting with aromasin, then there has to be an absolute connection between the ratio of E2 and DHT, not just Test and DHT. I will continue on Flomax, probably, but I'm not certain I will yet.
I know I didn't really answer anyone's questions, but in all honesty I don't know the answers, and apparently neither does my doctor. I could just stay on 200mg a wk and remain pretty healthy, but I'm curious now and want to know. As a side note, dropping down to 200mgs a week made very little difference from blasting at 1gram. My lifts are the same, but I can feel it more in my joints. My weight is the same. Any input would be welcomed. But remember, I'm a lot older than you guys and I don't have your resilience so your bodies are much more forgiving than mine. (I didn't re-read this, I just hit send, so sorry for any errors)
