i'm on epistane right now, day 22. i saw it kick in around week 2 at 30mg. u may want to start there to test your body's reaction but this is my first cycle. i'm at 40mg now and have leaned out pretty well; i'd make sure u stick to your disciplined diet otherwise u may put on a good amount of weight. Also I started taking furaz at only 150mg last thursday and felt like **** - my BP blew up for some reason, my face was red hot. so i stopped it after one day and feel fine now, so watch the combos. i space my dosing out from the time I get up to no later than 8pm if possible(i.e. 8am-10mg, 12pm-10mg, 4pm-10mg, & 8pm-10mg)- it may keep you up. and i've gotten some pumps/spasms in my back so have some taurine on hand as well.