Has anyone been on trt for 10 or more years

[vere76]

im concern with being prescribing testosterone replacement therapy is to be ineffective in the long-term treatment of aging. have you had to keep uping the dose?

 

[Presa]

Been "on" since 2007. Switched from gels to IM injections two years ago. Haven't had any issues. But, one time my doctor had me go "off" for a month to get a new baseline and my total T was 190. I felt like complete crap and hated the world. Never again will I go "off" test.

 

[Gutterpump]

If you stay in a healthy range, you shouldn't need to up the dose. That only occurs if you're constantly overloading your androgen receptors (ie: going over the range). This overtime, will downregulate the AR.

You can always look into l-carnitine-l-tartarate (LCLT) to help prevent this.

I occassional go 'off' by going onto HCG monotherapy. Once a year or so I've done this since starting. I wouldn't recommend it though honestly, unless you are really in tune with your body.