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Hairygrandpas log, fat- and older people welcome!- diet, training, cycles, healing

HIT4ME said:
Niacinamide ....which is a metabolite of niacin (nicotine acid) has been shown in studies to help with arthritis. It probably helps blood flow to the joints which improves healing, but it also seems to relieve pain. I believe it was used at 3 g a day...but it is cheap enough.
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MedRat said:
Thanks for that HIT4ME, I just finished order 100+ grams of Niacinamide. I'll try 2-4 grams per day to see how it goes. Anyone interested in knowing can PM me. I'm all for helping out other people.
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I'm taking niacin on- and off for almost 10 years now. It lowers triglycerides very well and straightens out my lipid profile. It did not help my joints and it can trigger gout attacks.
For a lot of people, the niacin rash isn't tolerable, for my part, I love it! Do not take more than 2 grams for a prolonged time, read about it first.
 
hairygrandpa said:
I'm taking niacin on- and off for almost 10 years now. It lowers triglycerides very well and straightens out my lipid profile. It did not help my joints and it can trigger gout attacks.
For a lot of people, the niacin rash isn't tolerable, for my part, I love it! Do not take more than 2 grams for a prolonged time, read about it first.
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Niacinamide isn't niacin. It doesn't cause a flush and won't effect triglycerides like niacin. Niacin itself doesn't seem to have data suggesting it would be useful for arthritis.

It is kind of like how agmatine is a metabolite of arginine and does a lot of the same stuff, but not all of it and also does things that arginine doesn't.
 
HIT4ME said:
Niacinamide isn't niacin. It doesn't cause a flush and won't effect triglycerides like niacin. Niacin itself doesn't seem to have data suggesting it would be useful for arthritis.

It is kind of like how agmatine is a metabolite of arginine and does a lot of the same stuff, but not all of it and also does things that arginine doesn't.
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Ah, okay! Got it!
 
Ill do more research. I read the report on joint health at up to 4 grams a day. I'll def keep the doses lower then. Time to do more reading. Heard back from a source on the NR. They want 4700/KG.
 
As of today, no supplement has helped with my knees. I took at least 10-15 different ones.
Next approach is BPC , horse -and dog medicine, nicotinamide have to wait. :)

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hairygrandpa said:
Ah, okay! Got it!
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Lol, the sides should still be considered. But I'm not an old fart and don't worry about things like gout. Really? Who has gout?
 
hairygrandpa said:
As of today, no supplement has helped with my knees. I took at least 10-15 different ones.
Next approach is BPC , horse -and dog medicine, nicotinamide have to wait. :)

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Have you tried Joint Force by Epharm?
 
MedRat said:
I'll tell you how Nicotinamide works for me. Srsly looking forward to your BPC log.
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Will see if I'm getting Adequan with my vet first, the BPC will need at least 2 weeks to arrive. As I understood, Adequan is injected IM once a week at 200-300mg. Monday is my testosterone shot (a 70 year old nurse does it for about US5), Maybe I have the Adequan on Monday and the adventure begins.

HIT4ME said:
Lol, the sides should still be considered. But I'm not an old fart and don't worry about things like gout. Really? Who has gout?
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I had my last attack 2 years ago. Believe me not funny! I was very determent to cut my own foot off once, the pain is crazy.
 
hairygrandpa said:
Will see if I'm getting Adequan with my vet first, the BPC will need at least 2 weeks to arrive. As I understood, Adequan is injected IM once a week at 200-300mg. Monday is my testosterone shot (a 70 year old nurse does it for about US5), Maybe I have the Adequan on Monday and the adventure begins.



I had my last attack 2 years ago. Believe me not funny! I was very determent to cut my own foot off once, the pain is crazy.
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Sorry to make light of your pain. But ...only a little :)

hairygrandpa said:
I have zero confidence it will make a difference, don't make me list the stuff I tried, it's endless, LOL.
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I wouldn't be so confident. I have a 350 pound father who can barely walk that says it is the only thing that helps. I have a 90 yo grandmother that can't stand up barely and is on opiates. She uses joint force and it is better than the lidocaine patches she says. It is good for acute pain...but only lasts 1-2 hours. Still better than nothing and it is cheap enough.

Excited to see your log.
 
HIT4ME said:
I wouldn't be so confident. I have a 350 pound father who can barely walk that says it is the only thing that helps. I have a 90 yo grandmother that can't stand up barely and is on opiates. She uses joint force and it is better than the lidocaine patches she says. It is good for acute pain...but only lasts 1-2 hours. Still better than nothing and it is cheap enough.

Excited to see your log.
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Its a trans dermal spray, interesting... but.... nah...
That are all small caliber weapons, I go for the nukes now.
 
Wow hairygranpa, the pics of your transformation are amazing. I mean nothing short of amazing.

On a side note, that is your closet? Holy **** batman can I move in?
 
Quest said:
Wow hairygranpa, the pics of your transformation are amazing. I mean nothing short of amazing.

On a side note, that is your closet? Holy **** batman can I move in?
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Thank you! Welcome Quest!
Yes you can move in. But you have to work for that, like carrying me around on your back, because my knees are "kaputt". LOL
If you agree, I also may call you Hodor.
LOL
 
Arms demolition

Pull ups neutral grip / superset /push ups elevated+handles (20 sec pauses between sets)
pull 11
push 18
pull 10
push 20
pull 9
push 18
pull 9 rest pause 2 rest pause 2
push 16 rest pause 5 rest pause 4

Triceps push down rope
100lbs x7/9/7
62 lbs x15/17/15

DB one arm preacher curls tut 3.1.1
30lbs x18/18/15 <---- painful fugging exercise, love it!

Floor DB extensions
2x22lbs x30 rest pause 14
2x22lbs x30 rest pause 11
2x22lbs x30 rest pause 8

standing alternating biceps curls
2x55lbs x6
drop
2x44lbs x7
drop
2x38lbs x11
 
MedRat said:
This would have been a joint saver.
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For some for sure.
If you have looked at my workouts, I always suspected it to be true. Can't imagine what else would be broken, besides my knees, if I would have trained with heavy weights.
 
I've already started losing weight. I'm guessing I've got 20-30lbs to go. Fortunately, I don't have neurological damage. BPC sounds like it'd be the most encouraging.

I read what you said about nuclear level weapons. These are the kinds to try. I've seen so many supplements which were either completely ineffective or very low grade at a high price.
 
MedRat said:
I've already started losing weight. I'm guessing I've got 20-30lbs to go. Fortunately, I don't have neurological damage. BPC sounds like it'd be the most encouraging.

I read what you said about nuclear level weapons. These are the kinds to try. I've seen so many supplements which were either completely ineffective or very low grade at a high price.
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If you use tramadol for your back, google: Ge-132 / Germanium Sesquioxide. It makes tramadol more effective, you can cut the dose and it works longer.
I use Ge-132 to boost my immune system when I suspect I caught something, it's highly effective but very expensive. It has as a "side effect" the re-enforcing ability of opiates, just for your knowledge.
 
Thanks for the heads up on the catalyst for tramadol. I used to take that and meloxicam. Now I'm doing turmeric Tylenol and Advil. I'm alright usually if I'm careful through the day. I can keep the pain down to around the 4-5 level. I feel fortunate there was any neurological damage.
 
MedRat said:
Thanks for the heads up on the catalyst for tramadol. I used to take that and meloxicam. Now I'm doing turmeric Tylenol and Advil. I'm alright usually if I'm careful through the day. I can keep the pain down to around the 4-5 level. I feel fortunate there was any neurological damage.
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Do you have a brace -or corset? When using BPC I would try and stretch -or compress my column in a way that it can heal in a proper position, have you thought about it?
 
I've considered one of the braces you hang from a door. I need to get another MRI. I've gotten worse in the last year.
 
Chest/Back/Tris&Shrugs
rp=rest pause 10sec

BB Bench flat
220lbs x6 rp 2
200lbs x7 rp 4
135lbs x11 rp 7

Incline BB bench
110lbs x15 rp 7
135lbs x13 rp 4
175lbs x5 drop 155lbs x3 drop 135lbs x10

Pull ups BW 220lbs/ superset/ one armed cable triceps push down 28lbs
Pull:10
Push:22
Pull:8
Push:20
Pull:6
Push:17

Seated row 220lbs /superset/ DB shrugs 2x77lbs, slow-mo 3sec up/ 3sec down
Row:12
Shrug:18
Row:12
Shrug:16
Row:10
Shrug:15

Lat pull down
230lbs x7/7/7
drop 190lbs x8
drop 145lbs x10

cable flies tut 3.1.1
2x30lbs x14/12/11/10 rp 6

One arm DB behind neck triceps extensions tut 3.1.1
28lbs x11/10/9 rp 4
 
Went to different vets here in the capital, they don't sell "Adequan" nor "Pentosan", they never heard of it.
However, they have an Argentinian product called Artroglycan for IM, its chondriotin sulfate but I'm not sure if its the same as Adequan, I highly suspect it to be, though.

Tonight I'm driving to my farm. I know a vet there who is involved with all the rich landlords and their racing horses. Hopefully he can at least get me Pentosan.
 
Hairygrandpas log, fat- and older people welcome!- diet, training, cycles, he...

I'm going to go over to the Vet Clinic on base and tell them I need some "things" for my "Equestrian"

Think it'll work, HG?
 
sparks2012 said:
I'm going to go over to the Vet Clinic on base and tell them I need some "things" for my "Equestrian"

Think it'll work, HG?
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I suspect they wanna see the horse first, LOL
In my next post I will describe what happened to me, stay tuned.
 
Okay, I went to a vet-pharmacy talking to the owner who treats horses for the rich guys and asked him about "Pentosan".
Here is how it went:

Me: "Hi"
He: "Hi"
Me: Do you have Pentosan, an injectable for horses?
He: Looking at me for 3 seconds, then putting 3 different packages on the table and saying: "You mean steroids, right?"
Me: Looking at the packages with names like: Boldegan and Ganabol...shaking my head: "No, it's an anti inflammatory for horses."
He: taking the boxes from the counter, saying "Don't know what you are talking about."

Damn! I wanted an anti inflammatory and get offered steroids.
Finally, I bought from him Artroglycan it's a "Glycosaminoglycan" -or chondroitin sulfate with a low molecular weight, similar to Adequan, I guess.

Not really sure if I want to inject this right away, still investigating, having not found anyone who tried it on himself.

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MedRat said:
Thanks for the heads up on the catalyst for tramadol. I used to take that and meloxicam. Now I'm doing turmeric Tylenol and Advil. I'm alright usually if I'm careful through the day. I can keep the pain down to around the 4-5 level. I feel fortunate there was any neurological damage.
Click to expand...

Just another heads up - agmatine has been shown to reduce tolerance to opiods. I'm researching the germanium as suggested now - very interesting, but potentially toxic it looks like at first glance...also, it decreases MPS.
 
hairygrandpa said:
Okay, I went to a vet-pharmacy talking to the owner who treats horses for the rich guys and asked him about "Pentosan".
Here is how it went:

Me: "Hi"
He: "Hi"
Me: Do you have Pentosan, an injectable for horses?
He: Looking at me for 3 seconds, then putting 3 different packages on the table and saying: "You mean steroids, right?"
Me: Looking at the packages with names like: Boldegan and Ganabol...shaking my head: "No, it's an anti inflammatory for horses."
He: taking the boxes from the counter, saying "Don't know what you are talking about."

Damn! I wanted an anti inflammatory and get offered steroids.
Finally, I bought from him Artroglycan it's a "Glycosaminoglycan" -or chondroitin sulfate with a low molecular weight, similar to Adequan, I guess.

Not really sure if I want to inject this right away, still investigating, having not found anyone who tried it on himself.

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LOL, you should have taken the juice too!!
 
HIT4ME said:
Just another heads up - agmatine has been shown to reduce tolerance to opiods. I'm researching the germanium as suggested now - very interesting, but potentially toxic it looks like at first glance...also, it decreases MPS.
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Very toxic if its not GE-132. That's why it was banned by FDA in the past. Will look up Agmantine a bit, but I'm not really in need for opiates right now.
Need some courage to inject me the dog-meds, considering one-or two shots of Bourbon first.
 
Yeah, this GE-132 looks very interesting indeed. It is funny because I have a friend with Alzheimers, and I was researching that, made an agmatine connection, researched agmatine and found out that it may be useful in alzheimers but is also useful in opiod tolerance/management. Now, you suggest GE-132 and I see it may be useful in opiod tolerance, but I'm making connections to Alzheimers in the other direction. Too early for me to have a formed opinion, but it's definitely very interesting.
 
HIT4ME said:
Yeah, this GE-132 looks very interesting indeed. It is funny because I have a friend with Alzheimers, and I was researching that, made an agmatine connection, researched agmatine and found out that it may be useful in alzheimers but is also useful in opiod tolerance/management. Now, you suggest GE-132 and I see it may be useful in opiod tolerance, but I'm making connections to Alzheimers in the other direction. Too early for me to have a formed opinion, but it's definitely very interesting.
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I heard about Phosphatidylserine and alzheimers -and read about some nootropics to be useful.
 
I haven't been following the Alzheimer's information very carefully. I did see theres a breakthrough in treating one of the two causes. A drug which breaks down a specific protein in the brain?
 
MedRat said:
I haven't been following the Alzheimer's information very carefully. I did see theres a breakthrough in treating one of the two causes. A drug which breaks down a specific protein in the brain?
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There are so many paths that appear to be breakthroughs. Tau and Amyloid plaques are the hallmarks of the disease. A lot has been studied to break down these proteins, but I believe that we all create and eliminate these proteins on a regular basis. Something goes wrong with the "unfolding" of these proteins and they become resilient to breakdown in AD. Arginine deficiency in the brain has beeninked to this now too. Arginase inhibitors may have a role - norvaline, resveratrol are two natural inhibitors that come to mind. Agmatine. A metabolite of Arginase may help perform some of the functions of Arginase. Oral arginase does not cross the blood brain barrier, so just taking more arginase won't solve the issue. Agmatine does cross the BBB.

Agmatine also has been shown to improve response to pain killers, reduce tolerance to opiates, reduce the perception of pain itself, reduce anxiety and depression. All of these areas have some clinical overlap, which I don't u derstand and wonder if anyone really does.

For instance, pre-treating brain tissue with cortisol makes it more susceptible to drugs used to induce Alzheimer's. Studies show that periods of stress and sleep deprivation play a role in AD.

If I had a family history of AD or any concern, I would be trying to reduce cortisol levels, using Agmatine and taking an arginase inhibitor.

For pain, I am not sure why Agmatine has never been used in a joint supplement. Higher doses with some other supporting compounds may be effective and synergistic.
 
hairygrandpa said:
I heard about Phosphatidylserine and alzheimers -and read about some nootropics to be useful.
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I am not convinced any of the nootropics will aid in AD. At least none that I know of. It seems the first 10 years was focused on improving choline usage, the next 10 is focused on tau and Amyloid proteins, and now we have a few new directions that we could go in, but who really knows. There doesn't seem to be a solid pathology of what causes this disease, just a few hallmark symptoms.

I also wonder, based in the little research I have had time to look at, if PBC-157 may have some healing effects that could be helpful in AD. Many neurotransmitters are actually made in the gut. Not the brain , and we are just now figuring all of this out. Healing the gut with this peptide may have an indirect impact on AD? Who knows.
 
HIT4ME said:
I am not convinced any of the nootropics will aid in AD. At least none that I know of. It seems the first 10 years was focused on improving choline usage, the next 10 is focused on tau and Amyloid proteins, and now we have a few new directions that we could go in, but who really knows. There doesn't seem to be a solid pathology of what causes this disease, just a few hallmark symptoms.

I also wonder, based in the little research I have had time to look at, if PBC-157 may have some healing effects that could be helpful in AD. Many neurotransmitters are actually made in the gut. Not the brain , and we are just now figuring all of this out. Healing the gut with this peptide may have an indirect impact on AD? Who knows.
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Pulled some links up:

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I never researched AD, as I don't know anyone with the disease. I also read about the new findings MedRat mentioned and I bet it was on sciencedaily.com
 
Todays mission: moderate weights/shoulder burn out

rp= rest pause set 10sec

standing DB shoulder press

2x33lbs x20 rpx10 rpx8
2x33lbs x20 rpx10 rpx9
2x33lbs x20 rpx10 rpx7

standing DB bent over rear delt raises

2x44lbs x20 rpx10 rpx10
2x44lbs x15 rpx9 rpx7
2x44lbs x13 rpx10 rpx7

standing DB lateral raises

2x27.5lbs x15 rpx8 rpx8
2x27.5lbs x15 rpx9 rpx7
2x27.5lbs x15 rpx7 rpx6

ABS circuit:

Incline/roman chair leg raises/planking no pauses

Incline:38 Chair:14 Planking: 50sec
Incline:18 Chair:12 Planking: 30sec
Incline:13 Chair:10 Planking: 30sec

standing DB front raises

2x27.5lbs x15 rpx10 rpx10
2x27.5lbs x8 rpx10 rpx7
2x27.5lbs x8 rpx10 rpx8

Shoulders were rock hard after this, very good session.
 
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