GW1516...any first hand user experience?

Hey bro - got your PM. Never used this compound personally and dont know much more than what i read on wikipedia but it looks awesome. I requested some literature through my research lab (I run a chemical engineering group) from GalaxoSmithKline so I'll let you know what's what after I read up on this. Hell, maybe I can coerce a free sample from them.
 
O and the literature I found was for GW 501516 not GW 1516. Is that what you wanted?
 
CrazyChemist said:
O and the literature I found was for GW 501516 not GW 1516. Is that what you wanted?
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It`s the same thing. I don`t know why it`s listed with 2 different names. Maybe like some steroids, you can write it 2 different ways and it`s the same compound. But yes, that`s it.
 
Im very interested in this too guys....I am actually considering buying some and giving it a try

Mr.50
 
Hey I PM-ed you but for the forum I only read thru the abstracts but basically it looks like a promising compound and id love to give it a run. All the studies im seeing are 6 mos. or less so the long term sides arent well known. I need to read in detail the mechanism of action before i post more and unfortunately im working my ass off lately. When I get a sec i'll read them and post again.
 
CrazyChemist said:
Hey I PM-ed you but for the forum I only read thru the abstracts but basically it looks like a promising compound and id love to give it a run. All the studies im seeing are 6 mos. or less so the long term sides arent well known. I need to read in detail the mechanism of action before i post more and unfortunately im working my ass off lately. When I get a sec i'll read them and post again.
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Thanks, much appreciated.
 
reptone said:
Can`t ask for or name sources here. Anyplace you get your SERM/Research Chemicals should be able to help you out but it`s VERY expensive.
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One place is reasonable and they just had a sale over the weekend....also it was not clear if it was Buy 1 get 1.....so at that price I was going to buy some but again I would like to learn more....like how long of a run might be needed to see some favorable changes in body comp and fat utilization? and is there any long term risk from a 1-3 month run with it? (I know no one has long term info but even speculation would be something to think about at least)

Mr.50
 
Ok guys. Based on what I've read, GW1516 functions synergistically with AICAR and taking these two together is highly recommended. A 4 week cycle is what I would recommend but it may be the case that you can be on this drug indefinitely. I wouldn't suggest it until more studies come out.

The mechanism of action is actually quite outstanding. It appears that the compounds affect certain signaling pathways in the cell, activating exercise-related genes. Essentially, GW1516 might enable the user to expand the genetic matrix. Studies in rats indicated fat loss and muscle growth despite confining the rats to a space too small for adequate exercise.

The study touts the drug as "exercise in pill form". If I could get my hands on it id probly run a month course. Haven't found adequate infcormation on dosing but ill come back after more research.
 
CrazyChemist said:
Ok guys. Based on what I've read, GW1516 functions synergistically with AICAR and taking these two together is highly recommended. A 4 week cycle is what I would recommend but it may be the case that you can be on this drug indefinitely. I wouldn't suggest it until more studies come out.

The mechanism of action is actually quite outstanding. It appears that the compounds affect certain signaling pathways in the cell, activating exercise-related genes. Essentially, GW1516 might enable the user to expand the genetic matrix. Studies in rats indicated fat loss and muscle growth despite confining the rats to a space too small for adequate exercise.

The study touts the drug as "exercise in pill form". If I could get my hands on it id probly run a month course. Haven't found adequate infcormation on dosing but ill come back after more research.
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Problem with the AICAR is that it is very expensive and hard ot come by. The GW1516 is expense but it is available and not totally cost prohibative. There are studies that show the GW1516 works without the AICAR but only with exercise.

The real risk I am worried about it what effect does it have on muscle we dont really want to effect like cardiac tissue?

Mr.50
 
Also anyone have any idea what a normal does of GW1516 would be for a human per day? All at once or split up? I am thinking about giving it a run but I need to get an idea on dosages so I can figure out how much I need to get and if I can afford it?

Mr.50
 
“Drugs that improve health are not only going to be used by people who have medical problems. They may also be used by people who are healthy - or by athletes who want an edge,” said Evans. He noted that the sports world has long been aware of his lab's work demonstrating a link between PPAR-delta and endurance. What's more, GW1516 has a relatively simple chemical structure and can be synthesized easily. Evans anticipates that athletes will seek their own sources of the drug - if they haven't already.
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You'd think this would have a lot more buzz and that there'd be a plethora of logs by now.
 
Any new word on this? Heard from a distributor that they might start carrying it, but without some logs, stuff like dosing, timing, length of cycle, etc. are pretty tough to tell.

Would we even want to use something that shifts muscle focus to endurance? Or is it all good?

Sounded interesting regardless.
 
I ran it for a month

reptone said:
I`m looking for people that have actually used or knows someone and has seen results.
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I ran a log on another site, but can't post a link, due to being a new guy on here. At any rate, my resting heart rate went from 62 to 48, my cardio output went from about 27 calories per minute to 32 calories per minute. I was able to increase my cardio heart rate from 152 to 176 for a sustained 60 minutes. Not such a high cardio rate, I know, but I am 50, so its decent. My body fat went from 12% to 7% (measured by impedence and calipers)and my weight lifting went up about 20% both in weight used and reps. My timed mile, before was sub 5 minutes, but I got down as low as 4:20, and and during the last couple of weeks, I was able to consistently put in sub 4:30 miles.

The downsides I had, were some issues related to sexual arousal, kind of like what letro does to me. A little cialis and all was well. I also noticed a fluttering in my heart sometimes. I have had that happen years ago, but it returned several times while on GW1516. Overall, my impression is that its like a concentrated winstrol. Maybe 5 times as potent. I liked it, and intend to run it again, if I find myself slipping off of my numbers. The only point I'd make is to start really slow, and work your dosage up, SLOWLY so as not to harm yourself. Who knows, maybe this stuff will make your dick fall off in 5 years.
 
krogers58 said:
I ran a log on another site, but can't post a link, due to being a new guy on here. At any rate, my resting heart rate went from 62 to 48, my cardio output went from about 27 calories per minute to 32 calories per minute. I was able to increase my cardio heart rate from 152 to 176 for a sustained 60 minutes. Not such a high cardio rate, I know, but I am 50, so its decent. My body fat went from 12% to 7% (measured by impedence and calipers)and my weight lifting went up about 20% both in weight used and reps. My timed mile, before was sub 5 minutes, but I got down as low as 4:20, and and during the last couple of weeks, I was able to consistently put in sub 4:30 miles.

The downsides I had, were some issues related to sexual arousal, kind of like what letro does to me. A little cialis and all was well. I also noticed a fluttering in my heart sometimes. I have had that happen years ago, but it returned several times while on GW1516. Overall, my impression is that its like a concentrated winstrol. Maybe 5 times as potent. I liked it, and intend to run it again, if I find myself slipping off of my numbers. The only point I'd make is to start really slow, and work your dosage up, SLOWLY so as not to harm yourself. Who knows, maybe this stuff will make your dick fall off in 5 years.
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What was your dosing scheme?
 
I'd say search around(google) I have seen a few logs on this stuff and they are very positive.def have high hopes for this stuff and so far its delivering
 
Any new info on this stuff? Anyone else test it out? sounds very promising... well except the whole dick falling off part and all...
 
Krogers58, thanks for the only user-experience I've seen on this stuff. Any chance you can post your log (even without the link)? I'd love to see the numbers. Or at least share you dosage schedule. Thanks!
 
I read the log at ironmag, l want to see more, I am running a serious cut soon with albuterol, would love to add this if really legit
 
krogers58 said:
I ran a log on another site, but can't post a link, due to being a new guy on here. At any rate, my resting heart rate went from 62 to 48, my cardio output went from about 27 calories per minute to 32 calories per minute. I was able to increase my cardio heart rate from 152 to 176 for a sustained 60 minutes. Not such a high cardio rate, I know, but I am 50, so its decent. My body fat went from 12% to 7% (measured by impedence and calipers)and my weight lifting went up about 20% both in weight used and reps. My timed mile, before was sub 5 minutes, but I got down as low as 4:20, and and during the last couple of weeks, I was able to consistently put in sub 4:30 miles.

The downsides I had, were some issues related to sexual arousal, kind of like what letro does to me. A little cialis and all was well. I also noticed a fluttering in my heart sometimes. I have had that happen years ago, but it returned several times while on GW1516. Overall, my impression is that its like a concentrated winstrol. Maybe 5 times as potent. I liked it, and intend to run it again, if I find myself slipping off of my numbers. The only point I'd make is to start really slow, and work your dosage up, SLOWLY so as not to harm yourself. Who knows, maybe this stuff will make your dick fall off in 5 years.
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Nice
What was the dosage ? and how maytimes a day/week ? did you use? :)
 
Kroger I read your post. On ironmagazineforums.com, then research-chemicals, then 143600-gw1516-log.html. very informative. Has me seriously considering it.
 
i am into week 2 of GW... and I am down 1.1% bodyfat. i have had to tighten my belt a lil more to keep my pants up... it looks like its working so far... mroe to come.
 
Just reread this thread, will be looking for that article in the cycles section. Just ordered some gw1516 and aicar for my pet rat. Hoping to keep a log of his progress as well. I hope it will be of some value and not just a didn't work thread. Won't be till next end of next week I believe that he'll start his protocol.
 
TheEigthDwarf said:
Just reread this thread, will be looking for that article in the cycles section. Just ordered some gw1516 and aicar for my pet rat. Hoping to keep a log of his progress as well. I hope it will be of some value and not just a didn't work thread. Won't be till next end of next week I believe that he'll start his protocol.
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Post a link if you log it.
 
I've just completed my 3rd week on GW and am planning to run for another 5 weeks. I'm taking 5mg each day dosed once a day in the morning with my first meal.

My diet is a carb cycling based on Invalid Link Removed with Low, No and High carb days. The cycle I use is:

Sun/Mon/Wed/Thur/Fri - Low carb (2150 cals, 200g pro/200g carb/60g fat)
Tue - No carb (1750 cals, 220g pro/20g carb/80g fat)
Sat - High carb (2550 cals, 200g pro/300g carb/60g fat)

The cals change slightly as I eat different foods each day but the No carb days are always below 25g carbs and the Low carb days don't go above 200g carbs.

Training is:

Mon - Legs/Abs
Tue - Fasted LISS
Wed - Back/Shoulders
Thur - Fasted LISS
Fri - Chest/Arms
Sat/Sun - Off

Notes:

- There is a definite diuretic effect with this product as I lost almost 3lbs in the first 4 days. I also experienced some headaches and had to increase my water intake during this time.
- At 5mg the fat loss is slow and steady. In the 3 weeks I have used this product I have lost almost 3/4" on my waist and my shoulders/chest/arms are noticeably more vascular and leaner. I am at the stage where people are telling me that I am looking bigger as my arms are leaner so the muscles look bigger.
- There hasn't been any noticeable loss in strength and I have been able to slightly increase reps/weight with each session.
- So far there has been zero negative side effects other than the necessary increase in water intake during the first few days. If it hadn't been for the fat loss/increased vascularity I wouldn't even know that I was taking anything.
- Normally when I am cutting I will use a similar carb cycling diet except the calories would be a bit stricter (50g carbs less on Low carb days) and I would also add in one or two days of HIIT. Even with more calories and less cardio with GW I am losing fat quicker than I normally would and the extra calories allow me to retain and gain a small amount of strength.
- I haven't noticed any increase in cardio endurance but I am only doing 2 days of LISS per week.

I don't think this product is the silver bullet that it is touted as on some of the more hardcore sites but, with a decent diet and training program, it can certainly increase the fat loss. I'm going to run this product until mid-September, which will be for a full 8 weeks so I'll post the complete results then.
 
thanks for the info!! greatly appreciated on this, i guess i am taking the proper dose? .5ml (from a 150mg x 30ml) ?
also i am on cycle of Andro Lean v1 and went from 154lbs to 148 lbs in 2 weeks on...
guess we dont have to worry about gyno on gw?
 
You will need to check the site that you bought the GW from to check the dosage. Mine mentions 5mg/ml but I have also seen other sites that list it at 10mg/ml. This sounds like your product as 0.5ml would be 5mg, which is the normal dose and it sounds like you have already made some good progress.

There aren't any worries with gyno on GW. The only known problems are that it can increase slow twitch muscles, which mean that you would increase endurance but lose strength and also it led to an increase in intestinal polyps in mice that were predisposed to polyps. I can't remember if there was any dosage or length of usage mentioned in the intestinal polyps study but unless you have a family history of bowel/colon cancer issues or you use a large dosage for a long time you should be ok.

In either case I can't see 5mg for 8 weeks causing any issues and there have been some logs on the hardcore sites with people running 5mg or even 10mg for 16 weeks without any known negative side effects.
 
thanks all, i'll up it to 10 this evening. guess it wouldnt be a good idea to find sterile water locally would it? need for the aicar (and also the sleep inducing peptide both from precisionpeptixxs dot com.) notice 1 is solid the other is powder, do you just put the water in and shake? - stupid question i guess) found the info - vial GW1516 30ml. 5mg x ml. 150mg x vial.
 
Let me know how you get on with 10mg per day. I've seen some logs of more fat loss at 10mg but there can also be some side effects. For the moment I'm going to stick with 5mg as I am happy with the rate of fat loss and without any side effects.
 
asianfreak said:
thanks all, i'll up it to 10 this evening. guess it wouldnt be a good idea to find sterile water locally would it? need for the aicar (and also the sleep inducing peptide both from precisionpeptixxs dot com.) notice 1 is solid the other is powder, do you just put the water in and shake? - stupid question i guess) found the info - vial GW1516 30ml. 5mg x ml. 150mg x vial.
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Some peptides you don't shake because they will break apart. You'll have to look it up. Buy bacteriostatic water online and use that. Possibly available at pharmacies, I'm unsure
 
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