WesleyInman
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This is one of the hardest hitting products we have. Use this solo or it compliments HRT so well.
Use code "WES15" at checkout for 15% off any order!!
Extreme Muscle Mass Gainer†
Supports Testosterone Levels†
Balances Estrogen Levels†
Supports Lean Muscle Mass†
Helps Strength & Power†
Supports Aggression†
Helps Muscle Recovery†
GUARANTEED ABSORPTION. NO NEEDLES, NO PILLS, NO LIVER STRESS!†
Prohormones – Topical vs. Oral Administration
Although comparable to oral-dosage forms in efficacy, topical creams have numerous advantages over oral forms. First, topical administration avoids the first-pass effect of metabolism associated with the oral route. Therefore, topical administration allows for much higher and improved bioavailability. Second, topical administration allows prolonged release of prohormone compounds, which can improve adherence. Third, topical administration minimizes adverse effects due to lower prohormone peak concentrations. Prohormones are very effectively removed by the liver when taken orally. This means that much higher doses, ten to twenty times higher, must be taken when administering prohormones orally, as compared to topical administration that avoid the first pass effect of the liver.†
ACTIVE INGREDIENTS
(Per 2 Pumps)
4-DHEA is a naturally occurring DHEA isomer. It’s structure closely resembles regular DHEA but the double bond in the 4th position dramatically changes its effects. 4-DHEA is both very anabolic and androgenic, users report to experience tremendous increases in lean muscle mass with quickly followed by strength gains.†
R-DHEA
R-DHEA is a natural metabolite of dehydroepiandrosterone (DHEA) via the 5α-reductase enzyme, it may also appear under the name 3b-hydroxy-etioallocholan-17-one. R-DHEA can be found naturally occurring in most mammals and is excreted in urine as a normal part of human metabolism. It provides health benefits such as weight loss, muscle growth, and supports immune system function. R-DHEA does not aromatise into estrogen so bloating and gynecomastia should not be a concern. This compound is especially good for strength, muscle density and definition which makes it great to use during a cutting cycle or alongside a prohormone that helps build mass during a bulking phase for a balanced strength and size stack.†
1-DHEA
5-DHEA
5-DHEA has been popular in the life extension crowd since the 1980’s. It’s typically used for its ability to support energy and general well being. More recently higher doses of 5-DHEA have been used to improve body composition due to DHEA’s mild anabolic and thermogenic effects. This makes 5-DHEA an excellent choice for cutting during a calorie deficient diet since 5-DHEA has good muscle sparing properties.†
7-Keto DHEA
7-Keto-DHEA is a prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). 7-keto-DHEA helps speed up the metabolism and heat production to promote weight loss. It also helps to improve lean body mass and build muscle, increase the activity of the thyroid gland, boost the immune system, enhance memory, and slow aging.†
Clinical Research for 7-Keto DHEA
ABSTRACT
A randomized, double-blind, placebo-controlled study of 3-acetyl-7-Keto-dehydroepiandrosterone in healthy overweight adults
Objective
The purpose of this study was to determine the effects of 3-acetyl-7-Keto-dehydroepiandrosterone (7-Keto DHEA) in healthy overweight adults.
Methods
In a double-blind, placebo-controlled protocol, 30 adults (28 women and 2 men; mean age, 44.5 ± 11.5 years) with a mean body mass index of 31.9 ± 6.2 kg/m2 were randomly divided into 2 groups of 15: Group 1 received 7-oxo-DHEA 100 mg twice daily and Group 2 received placebo for 8 weeks. All subjects participated in an exercise training program 3 times per week. Each exercise session consisted of 60 minutes of cross-training (aerobic and anaerobic exercise) under the supervision of an exercise physiologist. In addition, each subject was instructed to follow a diet of ~1800 kcal/d (20 kcal/[kg · d]) by a registered dietitian. Subjects received biweekly dietary counseling to encourage compliance. Study participants underwent serum multiple-assay chemistry testing, as well as body composition, blood pressure, and dietary analysis at baseline, week 4, and week 8.
Results
Of the 30 subjects who entered the study, 23 completed the 8-week protocol. Seven subjects dropped out for personal reasons unrelated to the study. Group 1 lost a significant amount of body weight compared with Group 2 (−2.88 kg vs −0.97 kg; P = 0.01) over the 8 weeks. Group 1 also achieved a significant reduction in body fat compared with Group 2 (−1.8% vs −0.57%; P = 0.02). The rate of change in body fat per 4-week interval in Group 1 was 3.1 times that in Group 2 (−0.88% vs −0.28%; P < 0.01). Group 1 also experienced a significant increase in triiodothyronine (T3) levels compared with Group 2 over the 8-week study period (+17.88 ng/dL vs 2.75 ng/dL; P = 0.04). There were no significant changes in levels of thyroid-stimulating hormone (TSH) or thyroxine (T4) in either group. In addition, no significant changes were observed in vital signs, blood sugar, testosterone and estradiol levels, liver and renal function, or overall caloric intake during the study. No subjective adverse effects were reported throughout the study.
Conclusions
The results of the study suggest that 7-Keto DHEA combined with moderate exercise and a reduced-calorie diet significantly reduces body weight and body fat compared with exercise and a reduced-calorie diet alone. In addition, 7-Keto DHEA significantly elevated T3 levels but did not affect TSH or T4 levels, indicating that it does not adversely affect thyroid function in the short term.
https://www.sciencedirect.com/science/article/abs/pii/S0011393X00800260
Androsta-3 5-diene-7 17-dione
Androsta-3 5-diene-7 17-dione is an aromatize inhibiting compound and is a DHEA analog that will help to reduce estradiol and is mostly used as a post cycle therapy. Androsta-3 5-diene-7 17-dione which helps with decreasing in circulating levels of estrogen in the body. Simply put it will help inhibit or reduce the amount of androgens in the body that can convert into estrogen. Androsta-3 5-diene-7 17-dione is a suicide aromatase inhibitor, meaning that it binds to the aromatase enzyme and can not be reversed.†
Gear Cream Topical Delivery System
For best results apply 1 pump of GEAR Cream twice daily (1 pump in AM & 1 pump in PM) to the upper arms, shoulders/traps, thighs or abdominal areas. Ensure the areas are clean and free from excessive hair, avoid showering or swimming for at least 8 hours after application.
Use code "WES15" at checkout for 15% off any order!!
Extreme Muscle Mass Gainer†
Supports Testosterone Levels† Balances Estrogen Levels† Supports Lean Muscle Mass† Helps Strength & Power† Supports Aggression† Helps Muscle Recovery†GUARANTEED ABSORPTION. NO NEEDLES, NO PILLS, NO LIVER STRESS!†
Prohormones – Topical vs. Oral Administration
Although comparable to oral-dosage forms in efficacy, topical creams have numerous advantages over oral forms. First, topical administration avoids the first-pass effect of metabolism associated with the oral route. Therefore, topical administration allows for much higher and improved bioavailability. Second, topical administration allows prolonged release of prohormone compounds, which can improve adherence. Third, topical administration minimizes adverse effects due to lower prohormone peak concentrations. Prohormones are very effectively removed by the liver when taken orally. This means that much higher doses, ten to twenty times higher, must be taken when administering prohormones orally, as compared to topical administration that avoid the first pass effect of the liver.†
ACTIVE INGREDIENTS
(Per 2 Pumps)
- 75mg 4-DHEA
- 75mg R-DHEA
- 75mg 7-Keto DHEA
- 50mg 1-DHEA
- 50mg 5-DHEA
- 30mg Androsta-3 5-diene-7 17-dione
- 100 Pumps Per Bottle
- Suggested Dose is 2 Pumps Daily
4-DHEA is a naturally occurring DHEA isomer. It’s structure closely resembles regular DHEA but the double bond in the 4th position dramatically changes its effects. 4-DHEA is both very anabolic and androgenic, users report to experience tremendous increases in lean muscle mass with quickly followed by strength gains.†
R-DHEA
R-DHEA is a natural metabolite of dehydroepiandrosterone (DHEA) via the 5α-reductase enzyme, it may also appear under the name 3b-hydroxy-etioallocholan-17-one. R-DHEA can be found naturally occurring in most mammals and is excreted in urine as a normal part of human metabolism. It provides health benefits such as weight loss, muscle growth, and supports immune system function. R-DHEA does not aromatise into estrogen so bloating and gynecomastia should not be a concern. This compound is especially good for strength, muscle density and definition which makes it great to use during a cutting cycle or alongside a prohormone that helps build mass during a bulking phase for a balanced strength and size stack.†
1-DHEA
5-DHEA
5-DHEA has been popular in the life extension crowd since the 1980’s. It’s typically used for its ability to support energy and general well being. More recently higher doses of 5-DHEA have been used to improve body composition due to DHEA’s mild anabolic and thermogenic effects. This makes 5-DHEA an excellent choice for cutting during a calorie deficient diet since 5-DHEA has good muscle sparing properties.†
7-Keto DHEA
7-Keto-DHEA is a prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). 7-keto-DHEA helps speed up the metabolism and heat production to promote weight loss. It also helps to improve lean body mass and build muscle, increase the activity of the thyroid gland, boost the immune system, enhance memory, and slow aging.†
Clinical Research for 7-Keto DHEA
ABSTRACT
A randomized, double-blind, placebo-controlled study of 3-acetyl-7-Keto-dehydroepiandrosterone in healthy overweight adults
Objective
The purpose of this study was to determine the effects of 3-acetyl-7-Keto-dehydroepiandrosterone (7-Keto DHEA) in healthy overweight adults.
Methods
In a double-blind, placebo-controlled protocol, 30 adults (28 women and 2 men; mean age, 44.5 ± 11.5 years) with a mean body mass index of 31.9 ± 6.2 kg/m2 were randomly divided into 2 groups of 15: Group 1 received 7-oxo-DHEA 100 mg twice daily and Group 2 received placebo for 8 weeks. All subjects participated in an exercise training program 3 times per week. Each exercise session consisted of 60 minutes of cross-training (aerobic and anaerobic exercise) under the supervision of an exercise physiologist. In addition, each subject was instructed to follow a diet of ~1800 kcal/d (20 kcal/[kg · d]) by a registered dietitian. Subjects received biweekly dietary counseling to encourage compliance. Study participants underwent serum multiple-assay chemistry testing, as well as body composition, blood pressure, and dietary analysis at baseline, week 4, and week 8.
Results
Of the 30 subjects who entered the study, 23 completed the 8-week protocol. Seven subjects dropped out for personal reasons unrelated to the study. Group 1 lost a significant amount of body weight compared with Group 2 (−2.88 kg vs −0.97 kg; P = 0.01) over the 8 weeks. Group 1 also achieved a significant reduction in body fat compared with Group 2 (−1.8% vs −0.57%; P = 0.02). The rate of change in body fat per 4-week interval in Group 1 was 3.1 times that in Group 2 (−0.88% vs −0.28%; P < 0.01). Group 1 also experienced a significant increase in triiodothyronine (T3) levels compared with Group 2 over the 8-week study period (+17.88 ng/dL vs 2.75 ng/dL; P = 0.04). There were no significant changes in levels of thyroid-stimulating hormone (TSH) or thyroxine (T4) in either group. In addition, no significant changes were observed in vital signs, blood sugar, testosterone and estradiol levels, liver and renal function, or overall caloric intake during the study. No subjective adverse effects were reported throughout the study.
Conclusions
The results of the study suggest that 7-Keto DHEA combined with moderate exercise and a reduced-calorie diet significantly reduces body weight and body fat compared with exercise and a reduced-calorie diet alone. In addition, 7-Keto DHEA significantly elevated T3 levels but did not affect TSH or T4 levels, indicating that it does not adversely affect thyroid function in the short term.
https://www.sciencedirect.com/science/article/abs/pii/S0011393X00800260
Androsta-3 5-diene-7 17-dione
Androsta-3 5-diene-7 17-dione is an aromatize inhibiting compound and is a DHEA analog that will help to reduce estradiol and is mostly used as a post cycle therapy. Androsta-3 5-diene-7 17-dione which helps with decreasing in circulating levels of estrogen in the body. Simply put it will help inhibit or reduce the amount of androgens in the body that can convert into estrogen. Androsta-3 5-diene-7 17-dione is a suicide aromatase inhibitor, meaning that it binds to the aromatase enzyme and can not be reversed.†
Gear Cream Topical Delivery System
- Dimethyl Isosorbide (DMI) – is a high purity solvent and carrier which offers a safe, effective delivery enhancement mechanism for the active ingredients in Gear Cream.
- Ethoxydiglycol – is a cosmetic grade solvent that conforms to the current USP/NF monographs. Ethoxydiglycol is particularly appropriate for skin care preparations where it acts as an excellent solvent and carrier.
- Propylene glycol – is an organic compound that is used 2 primary reasons. First, it has the traits of a humectant; it is able to absorb and help the skin retain moisture. Second, it helps active ingredients penetrate the skin.
- Glycerin – when used on skin works as humectant, which is why it attracts moisture onto your skin.
- Carbomer – helps to distribute and suspend the active ingredients in the Gear Cream.
- Triethanolamine (TEA) – Helps the water-soluble and oil-soluble ingredients blend better. TEA neutralizes fatty acids and solubilizes oils and other ingredients that are not completely soluble in water.
For best results apply 1 pump of GEAR Cream twice daily (1 pump in AM & 1 pump in PM) to the upper arms, shoulders/traps, thighs or abdominal areas. Ensure the areas are clean and free from excessive hair, avoid showering or swimming for at least 8 hours after application.