Guest viewing limit reached
  • You have reached the maximum number of guest views allowed
  • Please register below to remove this limitation

Found this at BB.com mestanolone

milwood said:
Anyone have a feeling on whether this would be a good thing to try if results from M5AA were NOT that impressive? Sledge, is this what you mean by "not for everyone". In other words, could this work for those for whom M5 DIDN'T seem too strong, or would that imply that this would be best avoided/probably not effective in such cases? Apologies if that sounds idiotic, but I know what I'm TRYING to say!
Click to expand...
I think he meant that because this is pretty hardcore, it is good that not everyone will rush out to use it, because of the potential side-effects. It will work for you. So would M5AA have worked for you, you probably needed a much higher dose. If it worked for East German olympic powerlifters, I seriously doubt you are immune.
 
Oh im sure it will work. Like Strategos said you may have needed a higher dose of m5aa, but this wont require a conversion to work.
 
If you run it, run a lot of Beta Sitosterol to protect your prostate--it's going to be more active there than your scalp.
 
It's well known that DHT is the principle androgen in the prostate, and that the prostate converts Test to DHT:

"dihydrotestosterone (DHT) is the principal androgen in the prostate"

"Testosterone is the major circulating androgen in blood and is converted to dihydrotestosterone (DHT)1 in the prostate by the enzyme 5Invalid Link Removed-reductase."

Grino, P.B. , J.E. Griffin , and J.D. Wilson (1990) Testosterone at high concentrations interacts with the human androgen receptor similarly to dihydrotestosterone. Endocrinology. 126: 1165-1172

The reason DHT blockers are prescribed for Prostate problems is because we know that inhibits Type II 5-reductase enzyme, and this reduces DHT conversion.

We also know that high levels of DHT causes BPH.

Proscar/Finasteride was developed for this reason. As an antecedant effect, DHT blockers have been shown to reduce balding by reducing circulating DHT.

However, there are many, many more DHT receptor sites in the prostate vs. the scalp.

Further, we know that DHT has very high RBA (relative binding affinity) in the prostate, and very low in muscle tissue.

We also have studies that show that M-DHT has a RBA of anywhere from 300% to 400% that of DHT.

"Relative binding affinity of anabolic-androgenic steroids: comparison of the binding to the androgen receptors in skeletal muscle and in prostate, as well as to sex hormone-binding globulin"
Endocrinology, Vol 114, 2100-2106, Copyright © 1984

So it goes without saying that your hair isn't as big a concern as your prostate should be. This compund is probably going to be very hard on the prostate, and that's why he's saying it's only for the hardcore. You need to be prepared, and you need to know what it does.

To wit: How many reports of balding have you heard from M5AA?
 
I knew that both the prostate and the scalp was the primary binding sites for DHT, and thus it could cause both BPH and hairloss, I just never knew that the prostate had so much more then the scalp. Good info Brodus, any recommendation for a good Beta-Sitosterol supp. or should one just mega dose on Saw P.
 
Yeah, I know about it b/c prostate issues run in the family and I've researched the hell out of it.

Beta Sitosterol is the active ingredient in Saw Palmetto.

Although I take SP everyday, you're better off taking Beta Sitosterol in this situation. You should take it for about a month before your cycle. I think 300-400mg. daily is what you want. You can get it rather cheaply. I'm going to get 100 grams of raw powder for making my own "superior ancillary blend." I might even sell it in the swap meet. It will be Beta Sis, NAC, Milk Thistle, ALA, and Hawthorne Berry.

And I say this not becuase I doubt MDHT-->much the opposite! M5AA was totally bad ass, and this is going to be 3X that...it's going to be insane! I'm afraid to take it b/c my grandfather died from Prostate cancer.
 
Rogue Drone said:
I meant to chime in on this DHT/Prostate connection, never got to it. Long story short, every man's at risk for prostate problems, and for every study that says DHT does'nt cause BPH, there are two that says it does.I'd wager that a fair number of MDHT users are going to need BS after a long and/or heavy cycle of this, after they notice the urinary and ejaculatory flow reduction.Natural Progesterone cream is a site specific way to block the DHT receptors in the Prostate.

Carry on, Brodus, as usual you're doing a good job.
Click to expand...

Ummmm, progesterone cream site specific?

Maybe I'm stupid here, but how is that administered?
 
if one is worried about prostate, would semi-frequent PSA test during bloodwork be enough to assure the Mdht isn't negatively affecting prostate?
 
You must log in or register to reply here.
Back
Top