Fertility
- Thread starter dinoiii
- Start date
dinoiii
Featured Author
Omigod! There is SO MUCH in these supplements, I would be hard pressed given the degree of interaction with many herbals and semen quality that something doesn't take effect...my only hope is that the quantities are so small because they kitchen-sinked it that it would be no more than wallet-slimming versus anything else.
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dinoiii
Featured Author
Wow - interesting that you still went to IUI. What reasoning did you have to not expect spontaneous insemination with these numbers? I don't know that IUI added a lot of value to this equation (compared with spontaneous). Of course, fertility people might tell you different but success rates with IUI are something to yawn at in most instances IMO.
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dinoiii
Featured Author
Interesting For Motility Woes
The antioxidant hormone melatonin may play a role in the production of healthy sperm, according to a new study. Previous research has shown that sperm contain melatonin and have melatonin membrane receptors, yet the relationship between melatonin and sperm health had not yet been determined. The American Society for Reproductive Medicine states that one-third of infertility cases among couples are due to male factors.
In this study, sperm from 52 men with impaired fertility was examined. The sperm was evaluated for concentration, motility and morphology (structure). In addition, the subjects were evaluated for urinary 6-sulfatoxy-melatonin and urinary total antioxidant capacity to determine if there was a correlation between the sperm parameters evaluated and melatonin and antioxidant status. In vitro, the sperm was exposed to melatonin and evaluated for changes in motility.
The results of the study showed that increased urinary levels of 6-sulfatoxy-melatonin and total antioxidant capacity correlated with increased sperm concentration, motility and improved morphology. In vitro, sperm treated with melatonin for 30 minutes showed increased sperm motility and an increase in the percentage of rapidly swimming cells.
The study concluded that melatonin improves semen quality. Based on the results of this research, it is likely that this unique antioxidant hormone plays a role in supporting sexual and reproductive health.
Reference:
Ortiz A, Espino J, Bejarano I, Lozano GM, Monllor F, García JF, Pariente JA, Rodríguez AB. High endogenous melatonin concentrations enhance sperm quality and short-term in vitro exposure to melatonin improves aspects of sperm motility. J Pineal Res. 2010 Oct 21. Published Online Ahead of Print.
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The antioxidant hormone melatonin may play a role in the production of healthy sperm, according to a new study. Previous research has shown that sperm contain melatonin and have melatonin membrane receptors, yet the relationship between melatonin and sperm health had not yet been determined. The American Society for Reproductive Medicine states that one-third of infertility cases among couples are due to male factors.
In this study, sperm from 52 men with impaired fertility was examined. The sperm was evaluated for concentration, motility and morphology (structure). In addition, the subjects were evaluated for urinary 6-sulfatoxy-melatonin and urinary total antioxidant capacity to determine if there was a correlation between the sperm parameters evaluated and melatonin and antioxidant status. In vitro, the sperm was exposed to melatonin and evaluated for changes in motility.
The results of the study showed that increased urinary levels of 6-sulfatoxy-melatonin and total antioxidant capacity correlated with increased sperm concentration, motility and improved morphology. In vitro, sperm treated with melatonin for 30 minutes showed increased sperm motility and an increase in the percentage of rapidly swimming cells.
The study concluded that melatonin improves semen quality. Based on the results of this research, it is likely that this unique antioxidant hormone plays a role in supporting sexual and reproductive health.
Reference:
Ortiz A, Espino J, Bejarano I, Lozano GM, Monllor F, García JF, Pariente JA, Rodríguez AB. High endogenous melatonin concentrations enhance sperm quality and short-term in vitro exposure to melatonin improves aspects of sperm motility. J Pineal Res. 2010 Oct 21. Published Online Ahead of Print.
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ripped_one
Member
Well, we did the IUI, then had sex a couple of times when we went home, then a couple of times a day for the next two days. Result? No pregnancy. Figured why not try everything, as she has to do injections to grow the egg, and the least we could do was try to maximize the chances.
We are taking a break this month (holidays, spending a month in Europe for vacation and business, etc), but next month we are going to try again. This time we are goign to try to grow at least 3 eggs instead of 1, so our chances go up.
ripped_one
Member
I'll get back on that melatonin tonight!
DaveGabe24
Well-known member
Hey Doc, I have the go-ahead to submit my first proposal to perform some of my own research in the andrology lab I work at in NJ. I wanted to run by my ideas with you before I submit them, if you have a sec to PM me, and we can discuss them a little, I'd really appreciate it!
The parameters I'm focusing on will be changes in motility and viability (eosin stains / hypoosmotic swelling test) via reduction of ROS in the microenvironment.
The parameters I'm focusing on will be changes in motility and viability (eosin stains / hypoosmotic swelling test) via reduction of ROS in the microenvironment.
DaveGabe24
Well-known member
In certain cases IUI's may help improve pregnancy as opposed to IC, I.E. viscous cervical mucus / seminal plasma, gels/debris, leukocytes, agglutination/clumping....which would all be washed allowing for a more concentrated sample to be inseminated.
Simply based on my experience, as I've had patients come in with samples that would predictably never lead to a spontaneous pregnancy outcome, and had success. I do agree though, with his numbers it would have been hard to justify IUI's, the only other thng I can believe is it may have been on his partners end, malformed uterus, endometriosis, cerv stenosis, etc. etc.? I am assuming its not PCOS or something hormonally related cause that would be spotted in her initial BW evals. I'd like to believe they didnt do it just for the $$...maybe that's just wishful/naive thinking on my part heh
Wellshii
New member
Good thread,bump for us who want kids.I actually wanted one last night,did the deed, and hope all is good. Ive been taking mucuna myself,my loads are pretty heavy compared to prior loads. Im just worried about the additive titanium dioxide in my vitamins. but then ,I eat really clean as does my wife.