Fenugreek

bigguns77

New member
Hey guys whats the deal with fenugreek? What does it actually do for you during a pct. Is it a test booster? I've done a search and had no luck in finding what purpose it serves.
 
...and it makes your cajones plump back up if you get shrinkage ...or that "I'm really cold" look down south while your on. :D
 
Isoleucine

Fenugreek is a natural source of 4-hydroxy Isoluecine -- this increases the ability to get glucose into muscle cells. Post workout is a perfect time to take some fenugreek (4g).

Quote:
The addition of fenugreek extract (Trigonella foenum-graecum) to glucose feeding increases muscle glycogen resynthesis after exercise.

Ruby BC, Gaskill SE, Slivka D, Harger SG.

Department of Health and Human Performance, The University of Montana, Missoula, Montana, U.S.A..

The purpose of this study was to determine the effects of ingesting an oral supplement containing 4-Hydroxyisoleucine (4-OH-Ile, isolated from fenugreek seeds [Trigonella foenum-graecum]) with a glucose beverage on rates of post-exercise muscle glycogen resynthesis in trained male cyclists. Following an overnight fast (12 hr), subjects completed a 90-minute glycogen depletion ride after which a muscle biopsy was obtained from the vastus lateralis. Immediately and 2 hours after the muscle biopsy, subjects ingested either an oral dose of dextrose (Glu) (1.8 g.kg BW(-1)) or 4-OH-Ile supplement (Glu+4-OH-Ile, including 2.0 mg.kg(-1) 4-OH-Ile with the same oral dose of dextrose) with a second muscle biopsy 4 hours after exercise. Post exercise muscle glycogen concentration was similar for both trials. Overall, there was a significant increase in glucose and insulin concentrations from time 0 throughout the majority of the 4-hour recovery period, with no significant differences between the two trials at any time point. Although muscle glycogen concentration significantly increased from immediately post exercise to 4 hr of recovery for both trials, the net rate of muscle glycogen resynthesis was 63% greater during Glu+4-OH-Ile (10.6+/-3.3 vs. 6.5+/-2.6 g.kg wet wt.(-1).hr.(-1) for the Glu+4-OH-Ile and Glu trials, respectively). These data demonstrate that when the fenugreek extract supplement (4-OH-Ile) is added to a high oral dose of dextrose, rates of post-exercise glycogen resynthesis are enhanced above dextrose alone.

PMID: 15719265 [PubMed - in process]
 
This was my worry of megadosing fenugreek....would it not have the possible of directing glucose into fat cells as well depending on what time of day it was taken?



Malek256 said:
Fenugreek is a natural source of 4-hydroxy Isoluecine -- this increases the ability to get glucose into muscle cells. Post workout is a perfect time to take some fenugreek (4g).

Quote:
The addition of fenugreek extract (Trigonella foenum-graecum) to glucose feeding increases muscle glycogen resynthesis after exercise.

Ruby BC, Gaskill SE, Slivka D, Harger SG.

Department of Health and Human Performance, The University of Montana, Missoula, Montana, U.S.A..

The purpose of this study was to determine the effects of ingesting an oral supplement containing 4-Hydroxyisoleucine (4-OH-Ile, isolated from fenugreek seeds [Trigonella foenum-graecum]) with a glucose beverage on rates of post-exercise muscle glycogen resynthesis in trained male cyclists. Following an overnight fast (12 hr), subjects completed a 90-minute glycogen depletion ride after which a muscle biopsy was obtained from the vastus lateralis. Immediately and 2 hours after the muscle biopsy, subjects ingested either an oral dose of dextrose (Glu) (1.8 g.kg BW(-1)) or 4-OH-Ile supplement (Glu+4-OH-Ile, including 2.0 mg.kg(-1) 4-OH-Ile with the same oral dose of dextrose) with a second muscle biopsy 4 hours after exercise. Post exercise muscle glycogen concentration was similar for both trials. Overall, there was a significant increase in glucose and insulin concentrations from time 0 throughout the majority of the 4-hour recovery period, with no significant differences between the two trials at any time point. Although muscle glycogen concentration significantly increased from immediately post exercise to 4 hr of recovery for both trials, the net rate of muscle glycogen resynthesis was 63% greater during Glu+4-OH-Ile (10.6+/-3.3 vs. 6.5+/-2.6 g.kg wet wt.(-1).hr.(-1) for the Glu+4-OH-Ile and Glu trials, respectively). These data demonstrate that when the fenugreek extract supplement (4-OH-Ile) is added to a high oral dose of dextrose, rates of post-exercise glycogen resynthesis are enhanced above dextrose alone.

PMID: 15719265 [PubMed - in process]
 
Max32 said:
This was my worry of megadosing fenugreek....would it not have the possible of directing glucose into fat cells as well depending on what time of day it was taken?
That has been my own speculation. Adapatation response (desensitization) has also not been ruled out.

To address both unknowns, I reserve fenugreek supplementation for post workout.
 
Yeah, as to the second concern, Dr D uses it at 1,2,3,and 4 grams per week respectively over a 4 week period, goes off for 2, and then starts over for that reason...
 
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