Experiences with DLPA? DL-Phenylalanine

[JYD]

What was your experience and why did you take it?

 

[nostrum420]

it's in 5hr Energy, isn't it?

 

[Sculptor]

I have some and have run it several times over the years. Seems to work well I initially and then I notice dampening of effects over time. This eventually turns into dopamine. The more I read, the more I learn that things like l-tyrosine, 5-htp, and Dlpa (all things that encourage serotonin and dopamine) will effect everyone differently. I really can’t say how dlpa will effect you but I’m starting to use the stuff I listed above periodically, like 2-3 times a week vs everyday. Messing with neurotransmitters can put things out of balance. I’m not trying to scare you or anything, it’s not like these are super powerful compounds but I’m starting to realize that it’s not stuff you necessarily want to use on the daily. Just my two cents.

 

[Sculptor]

Oh and to directly answer your question, I originally got into dlpa because it’s purported to help improve my mood and also to numb pain specifically in the back. As I said earlier, seems to help initially and then over time I almost feel like it starts to lower my mood.

 

[aaronuconn]

What was your experience and why did you take it?

Good mood boost when taken sparingly. I usually took 500mg DLPA with 200mg caffeine and 1-2g ALCAR. Great for training on an empty stomach, as well as for work/studying.

Feels similar to 1-1.5g Tyrosine in my opinion.

 

[aaronuconn]

What was your experience and why did you take it?

Good mood boost when taken sparingly. I usually took 500mg DLPA with 200mg caffeine and 1-2g ALCAR. Great for training on an empty stomach, as well as for work/studying.

Feels similar to 1-1.5g Tyrosine in my opinion.

 

[HIT4ME]

I have some and have run it several times over the years. Seems to work well I initially and then I notice dampening of effects over time. This eventually turns into dopamine. The more I read, the more I learn that things like l-tyrosine, 5-htp, and Dlpa (all things that encourage serotonin and dopamine) will effect everyone differently. I really can’t say how dlpa will effect you but I’m starting to use the stuff I listed above periodically, like 2-3 times a week vs everyday. Messing with neurotransmitters can put things out of balance. I’m not trying to scare you or anything, it’s not like these are super powerful compounds but I’m starting to realize that it’s not stuff you necessarily want to use on the daily. Just my two cents.

The more I read about neurotransmitters, the more I think we are missing large chunks of theory about how things work. Or maybe I just don't grasp it, but it seems to not make sense to me.

Wonder if anyone here has used agmatine to avoid the dampening effects of DLPA.

 

[StarScream66]

DLPA is a very interesting compound. The D isomer especially of Phenylalanine can prevent the breakdown of endorphins in the body and give you a pretty good mood boost. Obviously, there is a threshold because amino acids work via enzyme conversion so you reach a limit that you can't get past. You can buy D-Phenylalanine on it's own and it's likely to have a much better experience with it than DLPA.

Incidentally, I went back and dug up some old articles written on DLPA. This is a DLPA Profile:

D,L-Phenylalanine By Andrew Novick - BitBin

D,L-Phenylalanine By Andrew Novick Antidepressant drugs that modulate the neurotransmitters serotonin and norepinephrine can often take up to 6 weeks to produce substantial response. This delayed response phenomenon is one of the most commonly cited fl

bitbin.it

And here is another article entitled "Supplements for Depression" which includes the mention of DLPA.

Supplements for Depression By Andrew Novick - BitBin

Supplements for Depression By Andrew Novick L-Tyrosine L-Tyrosine is an amino acid naturally found in food that serves as the precursor to the neurotransmitters dopamine and noradrenaline. A deficit in dopaminergic and/or noradrenergic activity is

bitbin.it

Hope that helps,
-SS

 

[muscleman]

I tried DLPA for some time to help with fatigue etc but for me it kind of had a tendency to agitate me, I got energized but didnt feel balanced. I am not too well read but these things with glutamate receptors and certain substances might be at play here? Am about to try Mucuna Pruriens extract containing l-dopa to see if that might help with partially stress and stim use induced fatigue. Anyhow natural rest without stims will slowly help a little bit I hope

 

[muscleman]

Have been trying tyrosine that I find help a little bit with stims and especially when I started out taking it with guarana in the morning it gave a prolonged and balanced energy with less of a crash. Agmatine as well is also supposed to play a role with the glutamate receptors and of course they all play a role in the biochemistry circles of having neurotransmitters go around. I know for certain a professional biochemist who specializes in treating ADHD and autism that a combination of alcar and taurine can have good results. Come to think of it I should contact and ask about dosage. But in the end these are complicated biochemistry places taking place within our bodies and nervesystems and everybody is unique and react slightly or more different to different substances

 

[muscleman]

I have some and have run it several times over the years. Seems to work well I initially and then I notice dampening of effects over time. This eventually turns into dopamine. The more I read, the more I learn that things like l-tyrosine, 5-htp, and Dlpa (all things that encourage serotonin and dopamine) will effect everyone differently. I really can’t say how dlpa will effect you but I’m starting to use the stuff I listed above periodically, like 2-3 times a week vs everyday. Messing with neurotransmitters can put things out of balance. I’m not trying to scare you or anything, it’s not like these are super powerful compounds but I’m starting to realize that it’s not stuff you necessarily want to use on the daily. Just my two cents.

Wisdom coming through here again Well when you start supplying something to the body in many cases the bodys reaction is to produce less of it on its own and as you say they all interact with each other if you start supplying one the balance with another one might be lost.

 

[StarScream66]

I forgot that I had a very interesting full study on DLPA if anyone is interested in reading it. I'll attach them here.

It's called "DL-phenylalanine markedly potentiates opiate analgesia – an example of nutrient-pharmaceutical up-regulation of the endogenous analgesia system"

 

[kisaj]

I've been on TRT for about 12 years now and it sounds like you may be low in pregnenolone and/or DHEA.

Regarding DLPA, it definitely has affect with regard to opioid recovery and assisting with neurotransmitter balancing, more so than l-tyrosine itself. DLPA and black seed oil really helped a lot when I was stopping kratom. Not like magic or anything, but I would say it helped speed up the "normalization" when stopping, especially in the PAWS period.

 

[muscleman]

Also quite interested in amino acids and the production of dopamine to get more motivation and increase focus and energy. I feel that tyrosine have been helping my stims last a bit longer without crash but they say in some the conversion of tyrosine to dopamine isn´t as efficient.
I Have some DLPA on the way in. I doo feel that alcar somehow help and it is supposed in some studies to help with energy and against depression and more and the older we get less production of dopamine and other neurotransmitters,
I also have some mucuna pruriens although it supposedly is riskier in the way it more directly converts to dopamine and then there will be risk of crash and desensitization to dopamine like with stim use.
Nootropics expert do have some basic information on aminoacids and some specifically to ADHD. But it isn´t all that straightforward since we all have our unique biochemistry and respond differently to different compounds.

 

[muscleman]

i am very interested in this ... almost bought some L-phenylalanine /DL-phenylalanine this week ... how is it treating you



I agree
I am very intrigued by neurotransmitters and am trying to learn more about them and how to optimize

I was on TRT for a couple years and never had the "well being" or "feel good" effect a lot of guys describe ... I even added low dose Primo to see if that would boost mood... if it did it was to a slight degree.

I have taken a few rounds of PH back in the day. One made me a sexual predator for about 2 months haha but never "elevated mood" ...

However, the thing that really turned me on to exploring the Dopamine-Testosterone connection is a combo pill I took a few years ago after an illness (before i began TRT). It was called Species Level 3 and it had quite the list of ingredients. Some on here said it was garbage but i felt so recharged while taking it. I think I slept better but also it was something else .. like the anabolics in the pill affected my brain chemistry in a way that made me more kind, patient, and confident ... overall i was just happier. My sleep was very deep as well ...

Have you ever heard of this? Any guess as what was the "feel good" component?

I just googled up and found something called Species Level 3 beyonder, is that the one? It has quite a few compounds in it mk 677 and more unfortunately I would not have much idea about what in that formula did what.

 

[muscleman]

your post is well timed ... i do appreciate the insight. funny thing i was just researching Preg deficiency and its almost ver betim with my symptoms today. Fatigue. Low motivation. Low energy. Just bleh. and on top of that my memory has gone to sh**t in a hurry. Overall i am very frustrated ... just not my best self.

Blood Work? (Coming off TRT) - AnabolicMinds.com

I am going to get a lot of labs and was planning on using PrivateMD as a few of you have pointed me in their direction in the past (thank you) ... is there a current discount code for this or any other site? I am coming off TRT and going to follow up with a the Male panel, the SHBG test...

anabolicminds.com

I have those symptoms too, large reason from stress ADHD etc and that will also whack the neurotransmitters. Guess I am gonna look up preg and DHEA as well an dhow they play in. All these compounds affect as somehow in the game of biochemistry were we all have our own games with differents strengths and weaknesses in different team players. Somehow we need the various teamplayers or neurotransmitters to play along nicely

 

[BCseacow83]

I just googled up and found something called Species Level 3 beyonder, is that the one? It has quite a few compounds in it mk 677 and more unfortunately I would not have much idea about what in that formula did what.

Just an FYI if there is really M1T in there that product is on the same legal ground as anadrol and dbol, that is to say outright illegal. I am always blown away at how brazen some companies are. If you are a UGL that is one thing and they(hopefully) take steps for security but these openly selling supplement companies........man. LOL I suppose they figure well the FDA is clear on SARMS and legality so f&&k it lets toss M1T in there, what the hell right? lol Glad to see the 25mg laxo, lol now that's hardcore..............lol.

I would eat my arm with that much MK and anamorelin, not to mention how redundant including both is. LaserGoPewPew you are not staying on this all the time are you? I would hate to see your labs on that stack for any length of time. That is a very strong product and should be approached with caution IMO.

 

[kisaj]

your post is well timed ... i do appreciate the insight. funny thing i was just researching Preg deficiency and its almost ver betim with my symptoms today. Fatigue. Low motivation. Low energy. Just bleh. and on top of that my memory has gone to sh**t in a hurry. Overall i am very frustrated ... just not my best self.

Blood Work? (Coming off TRT) - AnabolicMinds.com

I am going to get a lot of labs and was planning on using PrivateMD as a few of you have pointed me in their direction in the past (thank you) ... is there a current discount code for this or any other site? I am coming off TRT and going to follow up with a the Male panel, the SHBG test...

anabolicminds.com

Not sure if you are on TRT, but if so, it lowers progesterone a lot in men and while Pregnenolone can help as part of it converts, some men need to supplement. My specialists said it is now the most common addition to TRT in their male clients.

 

[kisaj]

i was for about 3 years ... i stopped a few months back and began clomid treatment to increase fertility as we are now trying to get preg

whats crazy is i have not heard this from many docs - none that treated me nor the PA i met with. i am glad I am looking into it now

Sorry if I wasn’t clear, but I am referring to Progesterone being the most common now.

i was for about 3 years ... i stopped a few months back and began clomid treatment to increase fertility as we are now trying to get preg

whats crazy is i have not heard this from many docs - none that treated me nor the PA i met with. i am glad I am looking into it now

If you can afford it, it would probably be helpful to test for Preg, progesterone, and DHEAS to see where you are. Progesterone is very important for sleep, mood, and anxiety.