Assuming a competent carrier, TD (or Sub-lingual) beats swallowed, any day of the week - No first pass liver breakdown. The trick is figuring out dosage: Yes, you need less, but you still need an effective amount. Most of the stuff is prop blended, so you don't even know how much of the compound is in each "serving" so to speak, and even if you could find out, you still need to figure out if it's enough. I don't know if anyone has those answers.
goodvibes ran Tridermal, so maybe he can chime in what he thinks following label recommendations would do (I think he ran double the label).