Ecdysterone?

ChuckRD said:
Yes, all the reading is fine and dandy, but I want to know WHY is it increasing nitrogen retention or how is it doing this. I will find out or at least hope I find out. I will keep everyone posted.
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Yea, I could never find out why, or the science behind it. Anyways, keep up posted! :hammer:
 
yep it affects ribosome function in the muscle cells, leading to faster muscular recovery and repair. Its also supposed to have other positive properties, including increased oxygen uptake in the blood, which is of interest for stamina training.
 
ryanbodybuilder said:
sorry jkeith....I didn't know your name..I am truly sorry....so when is this product coming out? I am all natural now for the next 2 years or more!!!
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It is ok :D

I joined Scivation in November and am the new board rep I guess (I don't feel new anymore, but part of the family). Call me Josh.

As far as timing, Marc says we are getting very close, so expect an update in the next week or so. :D
 
awesome nice to meet you josh..love your products and looking forward to this new ecdy product! I would like to be considered for a tester as I am all natural(as of late), clean and will give you a very meticulous log with updates daily...
 
ryanbodybuilder said:
awesome nice to meet you josh..love your products and looking forward to this new ecdy product! I would like to be considered for a tester as I am all natural(as of late), clean and will give you a very meticulous log with updates daily...
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Awesome man. At AM I don't know if Derek will handle the testing or I will, but needless to say we know you have an interest and it will be noted. :D
 
If it's even better than the usual ecdy, this should make for a nice PCT addition as well as a bridge. I could use that starting in mid March.

Hint hint, nudge nudge ;)
 
bioman said:
If it's even better than the usual ecdy, this should make for a nice PCT addition as well as a bridge. I could use that starting in mid March.

Hint hint, nudge nudge ;)
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Wolverine was always my favorite X-Men character. :D
 
bioman said:
I believe it ramps up ribosomal protein synthesis or metabolism...been a long time since I read up on it.
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Beast came across this...."ECDY acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP) to cause a positive nitrogen
balance in the body". NOW, mind you, USP is ONLY in insects but he did further research and found that RXR (retinoid X receptor) is the same thing in mammals. We stumbled across a GREAT paper indicating its nitrogen effect, increase in sex drive, reduction in cortisol and a major action as an adaptogen. All cited references that we will be getting to anaylze the data and methodologies. Great Stuff!!!!
 
I beleive it too. I used it stacked with Rhodiola for mountain climbing over the period of one summer. I did lose some LBM..which is totally unavoidable IMO..but I stayed lean and pumped the whole time. I had great energy and recovered almost as fast as an AAS cycle. It is IMO great stuff and if someone gets a high quality extract out that is priced well enough for me to use it all the time, I most certainly will.
 
bioman said:
I beleive it too. I used it stacked with Rhodiola for mountain climbing over the period of one summer. I did lose some LBM..which is totally unavoidable IMO..but I stayed lean and pumped the whole time. I had great energy and recovered almost as fast as an AAS cycle. It is IMO great stuff and if someone gets a high quality extract out that is priced well enough for me to use it all the time, I most certainly will.
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Well get ready because its coming. i have been preaching this to Scivation since I signed on and now its coming true. I actually stumbled across 2 other ingredients with similar activity....shall be interesting to see after i search on them.
 
Wow, I really hope this product ends up panning out.

I trust Thermolife's product, but I frankly don't want to drop $250 for a month's supply of Ecdysterone.
 
Reggin said:
Wow, I really hope this product ends up panning out.

I trust Thermolife's product, but I frankly don't want to drop $250 for a month's supply of Ecdysterone.
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lol, it isn't 250.
I am looking forward to seeing how well the cyanotis vaga works in this product
 
Reggin said:
It is if I want to take it at the recommended dosage.
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No, it is if you want to take it at an absurdly large dose that is not recommended by the company you are buying it from. You can take however much you want, but dont claim that thermolife recommends that you spend 250 a month, becuase this is totally false, and absolutely unnecessary in order to see results.
 
"It's interesting to note the amount of Ecdysterone these Soviet Studies used. According to Derek Cornelius, "Most of the experiments used 5 mg per kilogram of body mass per day as the dosage." To find out how much you would need to take to supply this same amount of ecdysterone, use this equation:

5 MG/KG X Your Weight = Dosage
Ex: 5 mg X 78 kg= 386 mg
 
Reggin said:
"It's interesting to note the amount of Ecdysterone these Soviet Studies used. According to Derek Cornelius, "Most of the experiments used 5 mg per kilogram of body mass per day as the dosage." To find out how much you would need to take to supply this same amount of ecdysterone, use this equation:

5 MG/KG X Your Weight = Dosage
Ex: 5 mg X 78 kg= 386 mg
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I know, i saw you post that at bb.com. But that doesn't change the fact that ThermoLife (the makers of the product you said would cost 250 for a month) do not recommend you using 25-35 caps per day. There are logs and personal reviews that clearly prove this wrong. I am sure taking that much would work, but why waste the money.

Not to mention we dont know what % extract or the type of ecdysterone he is referring to.

Either way, its a ridiculous claim to say that you need that much ecdysten for a month's supply, and it is very misleading.
 
italionstallion said:
I know, i saw you post that at bb.com. But that doesn't change the fact that ThermoLife (the makers of the product you said would cost 250 for a month) do not recommend you using 25-35 caps per day.
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I know this. But the resarch and your company say two different things. You guys say 9 caps/day (135 mg), while the resarch indicates that it should be 3-4x that amount.

There are logs and personal reviews that clearly prove this wrong. I am sure taking that much would work, but why waste the money.
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To validate the resarch claims in a real world setting.

Not to mention we dont know what % extract or the type of ecdysterone he is referring to.
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This is true. Although, I assume since it supposedly cost them thousands of dollars to extract it at the time, not to mention that they probably have access to top notch resources, that they would be using a very high quality extract (something similar to Thermolife's product, which I believe is very high quality)

Either way, its a ridiculous claim to say that you need that much ecdysten for a month's supply, and it is very misleading.
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Misleading to who? I am not a company rep, and do not speak for Thermolife. I am not trying to give anyone advice. I'm not saying I "need" that much. I have obviously stated before that such a dose isn't necessary to see results, but in an attempt to get the fantastic results that were achieved in human trials, I would be willing to replicate the experiment on myself.
 
Reggin said:
I'm not saying I "need" that much. I have obviously stated before that such a dose isn't necessary to see results, but in an attempt to get the fantastic results that were achieved in human trials, I would be willing to replicate the experiment on myself.
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I think that clarifies it very well. Thank you.
 
Syntrax's Syntrabol was dosed at 200mg a serving i was seeing gains at 600mg/day but the sweet spot was 1g a day.
 
CHAPS said:
Syntrax's Syntrabol was dosed at 200mg a serving i was seeing gains at 600mg/day but the sweet spot was 1g a day.
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I hit more than that when I tried it and still saw diddly, but it's possible the version I was using was of low quality too.
 
CDB said:
I hit more than that when I tried it and still saw diddly, but it's possible the version I was using was of low quality too.
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yeah i heard quality is a problem, but also the plant source it comes from from too.
 
sean_25 said:
yeah i heard quality is a problem, but also the plant source it comes from from too.
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As long as an adequate amount of the active ingredient is there, it shouldn't matter.
 
I am very interested in this product. When is the estimated release date? Where will it be available? Also, is there any word on the dosing of each ingredient, the number of doses per bottle, and the price?

I have had success with Fenotest, Sesamin, and LipidFX and found those to be very reasonably priced.
 
GrossSizeRocks said:
Also, is there any word on the dosing of each ingredient, the number of doses per bottle, and the price?
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Per Capsule, take 3 caps per day

100mg ACTIVE 20-beta-hydroxyecdysterone
100mg Rhodiola Rosea
50mg Bacopa Monnieri

30 day supply, so 90 capsules

Around $30
 
I bought a nasal spray that I was going to use for yombine after reading about it on avant. So I was thinking, since the oral-bioavability of ecdy is poor (I think) would it work intra-nasaly?
 
Xel said:
I bought a nasal spray that I was going to use for yombine after reading about it on avant. So I was thinking, since the oral-bioavability of ecdy is poor (I think) would it work intra-nasaly?
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Oral bioavailability is supposed to be fairly decent actually. Amounts of the active are what's at issue, and those seem to be pretty variable and low depending on the extract source, methods, etc.
 
Scivation said:
Per Capsule, take 3 caps per day

100mg ACTIVE 20-beta-hydroxyecdysterone
100mg Rhodiola Rosea
50mg Bacopa Monnieri

30 day supply, so 90 capsules

Around $30
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Marc,
How do you compare the potency of the extract that you use with the 20-beta-hydroxyecdysone (from rhaponcticum carthamoides) employed in the russian studies?
 
Syr said:
Marc,
How do you compare the potency of the extract that you use with the 20-beta-hydroxyecdysone (from rhaponcticum carthamoides) employed in the russian studies?
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Should be exactly the same. The chemical structure of the beta-hydroxyecdysterone is the same no matter what its source.
 
I mega-dosed ecdy a long time ago, and had some nice hardening. I only had enough to really go big for about 2 weeks, so any guesses about anabolism would most likely be useless.
 
diminuendo said:
I mega-dosed ecdy a long time ago, and had some nice hardening. I only had enough to really go big for about 2 weeks, so any guesses about anabolism would most likely be useless.
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The more and more info I come across, the more like ECDY not only for anabolic effect, but as an adaptogen as well. There are a few studies that show its excreted very quickly as well as catabolized so I feel that 100mg ACTIVE 3-5 times per day will be fantastic. Actually, with all of my athletes that took it for 6-8 weeks, responded very well with respect to strength, recovery and LBM.
 
bioman said:
Not to mention it's nice and clean..no side effects.
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Instead of extracting all these herbals, is there any way to synthesize the actives? Or would that somehow make them unnatural and subject to different regs?
 
CDB said:
Instead of extracting all these herbals, is there any way to synthesize the actives? Or would that somehow make them unnatural and subject to different regs?
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It would be much more expensive I would assume.
 
ChuckRD said:
The more and more info I come across, the more like ECDY not only for anabolic effect, but as an adaptogen as well. There are a few studies that show its excreted very quickly as well as catabolized so I feel that 100mg ACTIVE 3-5 times per day will be fantastic. Actually, with all of my athletes that took it for 6-8 weeks, responded very well with respect to strength, recovery and LBM.
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Mike's initial high-dose thermolife ECDY trial he loved combined with Marc's marketing is making me quite giddy about the product.

I don't usually get giddy about supplements.
 
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