the amount of protein he ingested can overload kidney and liver functions for one, and we should also keep in mind that his heart is probably not much bigger than ours, yet had to a lot of tissue to irrigate. One thing is known although many may think it is unrelated, it may still be to some extent--it's known that digestion breathing all generate free radical, thus eating very mammoth amount of cabs, proteins etc...sure generate more free radical than say in a caloric restricted individual--now free radicals it is known is linked to a lot of pathologies. Human biochemistry is ever so complicated, not to mention the role gene encoding has to play. One thing is for sure thoug, it's not uncommon to see either strong man and bodybuilders die at a young age, so there must be something there. Playing around with insulin, testosterone, GH/IGF-1 axis etc..etc..etc...can be fun at first but in the long term might in some individual terrible consequences--again supraphysiological levels of any hormone is bad, and it's common sense wen we think about it, just as too little can have as dramatic impact over time. I do not say that juicing alone send him to an early grave, but it a whole host a factors, including this, sure didn't help the poor guy. every bodily systems, organ, all of the nervous system, CNS, ANS, PNS etc... all work in unison, and losing balance is not that hard. As far as I'm concerned, as much as I like BBing, I want to remain natural for obvious reasons. Of course as I said I'm not huge, I'm 5'8'' 195 pounds, but I'm more after strength than being shredded....thus I should say that I'm more of a powerlifter. I however admire the impressive physique this guy Don achieved it'S amazing, but again it comes at a price. As long as one is aware of the risks involved of the possible consequences, then everything is fine.
I guess if he had a massive heart attack, he likely had clogged arteries--although there are another kind of heart attack that doen't involved clogged arteries.
Take for instance the GH craze--it's been seen by many as the end all of anti-aging, whereas it'S only a part of the puzzle. i'm much more interested in proper thyroid functioning, and cortisol control, than GH, although GH still has it's relevance, in fact they ALL play important roles in physiology.
Also on a more simplistic note, it's likely that pushing the human machine over it's normal capacity is possible, but it may create premature wear and tear--although it's not the same at all, take the instance of a car, if one constanly floor it engine being cold, course it will run this way and perform at 150% of it's capacity, but for how long ?