I haven't ran across a study showing that or lending evidence to that.
This is the thread I was referring to:
http://anabolicminds.com/forum/supplements/208839-blood-sugar-lowering.html
These are a few studies I found on PubMed.
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Iran J Reprod Med. 2014 Oct;12(10):695-704.
Reproductive toxicity of Momordica charantia ethanol seed extracts in male rats.
Tumkiratiwong P1, Ploypattarapinyo R1, Pongchairerk U2, Thong-Asa W1.
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Abstract
BACKGROUND:
Momordica charantia (M. charantia) seed has been supposed to have an antifertility property but mechanisms underlying the infertility effect have not been investigated.
OBJECTIVE:
We investigated the antifertility effect of M. charantia ethanol seed extracts on reproductive toxicology and seminal and plasma testosterone in male Wistar rats.
MATERIALS AND METHODS:
The control group (I) was provided daily 1 ml dimethylsulfoxide (DMSO) and the experimental groups II and III were given daily 400 and 800 mg dry matter/kg body weight of the extracts dissolved in 1 ml DMSO via the esophageal route. All groups were administered for 42 days (day 42). Changes in body weight, fertility, reproductive characteristics, testicular histopathology and levels of seminal and plasma testosterone among three groups were compared.
RESULTS:
On day 42, the extracts caused antifertility (p=0.001). The extracts demonstrated significant reductions in diameters of seminiferous tubules and epididymides, spermatid density, daily sperm production and caudal epididymal spermatozoa, sperm motility and viability (p=0.046). Pathological changes in seminiferous tubules revealed atrophy, desquamation, pyknosis nucleus and multinucleated giant cell. Plasma cells were evident in three parts of epididymides of rats treated with high dose of the extract. Furthermore, the high dose of the extract suppressed seminal testosterone level (p=0.001) and plasma testosterone level (p=0.002).
CONCLUSION:
Our data showed that high dose of M. Charantia seed extracts caused infertility in male rats. The interruption in their fertility was probably attributed to the direct toxic to seminiferous tubules, epididymis and the lowered testosterone level which might impact on sperm parameters.
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J Basic Clin Physiol Pharmacol. 2005;16(1):53-66.
Effect of graded doses of Momordica charantia seed extract on rat sperm: scanning electron microscope study.
Girini MM1, Ahamed RN, Aladakatti RH.
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Abstract
Morphological changes in sperm of albino rats observed under scanning electron microscopy illustrate the disturbance in the plasma membrane as well as in the acrosomal membrane on treatment with effect of graded doses of alcohol seed extract from Momordica charantia. Considerable changes in the shape and size of the sperm head were observed, with the middle region of the sperm head being slightly constricted dorsoventrally. Most sperm appeared morphologically abnormal in the mid-region of the tail, with formation of a balloon-like cytoplasmic droplet. The results of this study suggest that such effects may have resulted from a general disturbance in proteins and an alteration in the cauda epididymal milieu, probably due to androgen deficiency consequent to the anti-androgenic property of Momordica charantia seeds.
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J Ethnopharmacol. 1998 May;61(1):9-16.
Antispermatogenic and androgenic activities of Momordica charantia (Karela) in albino rats.
Naseem MZ1, Patil SR, Patil SR, Ravindra, Patil RS.
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Abstract
Petroleum ether, benzene and alcohol extracts of the seeds of Momordica charantia tested in rats at the dose level of 25 mg/100 g body weight for 35 days showed antispermatogenic activity as the number of spermatocytes, spermatids and spermatozoa was decreased. Increase in cholesterol level and Sudanophilic lipid accumulation indicates inhibition in the steroidogenesis. At the same time the weight of epididymis, prostate gland, seminal vesicle and levator ani was increased which showed its androgenic property. Out of the three extracts, the alcohol extract was more potent in its antispermatogenic, antisteroidogenic and androgenic activities.
