Do you need an AI with Paragon?

[bakerwil]

Does Paragon include an AI or should I run it with an AI?
Where if I used Intimidate for example, I would need to add an AI?

 

[dtrain13]

Does Paragon include an AI or should I run it with an AI?
Where if I used Intimidate for example, I would need to add an AI?

No. You could add a dose of Erase perhaps and get an Erase Pro type effect.

[h=3]Euonymus Alatus and Prunella Vulgaris Extracts[/h] Widely-used as Chinese herbal medicines, Euonymus Alatus and Prunella Vulgaris deliver a one-two punch to estrogen. Euonymous Alatus extract is a potent aromatase inhibitor with an IC50 of 11μm in Human placental aromatase. Animal studies have shown striking results: Treatment with EA extracts can lead to total estrogen deprivation in normal female rats. What's more, it displays selectivity for certain tissue types, and it may be much more selective and active towards aromatase enzymes expressed in breast tissue. This latter property may make it especially useful to people who are prone to gyno. It may be the most potent herbal aromatase inhibitor on the market today.

In contrast to Euonymus Alatus, Prunella Vulgaris interferes with estrogen receptor signalling indirectly. An unidentified compound within the extract binds to the aryl hydrocarbon receptor (AHR) as a full agonist, and this ligand-receptor complex seems to degrade the estrogen receptor protein via ubiquitin-mediated mechanisms. It seems to also compete with ER-mediated gene transcription via unknown mechanisms. One thing is certain: Estrogen is of no concern to anybody on Paragon!