DHEA

lboston

lboston

Well-known member
For those that use DHEA with their TRT protocol, what does your dosing schedule look like?

Also, what effects do you notice?
 
Iboston,

If your taking pills I would not do more then 25 mgs 2x's / day. For me and others I know it can drive up Estradiol E2 levels.

I found using a cream much better luck with Life Flo Health, DHEA for Men cream.
 
Invalid Link Removed is way better than barely digestable DHEA/Preg combo's in pill forms...dunno why people even still use that crap, it's outdated.
Invalid Link Removed
 
Also would suggest checking urine 24 hour DHEA to see if the TD DHEA is actually working
You can check in as little as 5-7 days. You may not see it in the blood ..
 
T-Bone said:
LMAO stop shilling. Dermacrine is 1000 times better and isn't from a sh*t company.
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Wow ....why don't you just tell the man what you really think about it... Lol ��
 
Joining the forum just to get views for your blog or to get more subscribers for your youtube channel just isn't right...Especially when there are sponsors that actually pay to be sponsors on here. It's pretty much stealing.
 
T-Bone said:
Joining the forum just to get views for your blog or to get more subscribers for your youtube channel just isn't right...Especially when there are sponsors that actually pay to be sponsors on here. It's pretty much stealing.
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I didn't, I joined to post reviews on sup's...if you see my first 50-60 are all related to reviews and the rest are helpful advice...but DHEA falls into the same category, doesn't it?
 
lboston said:
For those that use DHEA with their TRT protocol, what does your dosing schedule look like?

Also, what effects do you notice?
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25mg daily sublingual. Effects are numerous, but primarily energy, mental clarity, and some alpha feel.
 
Ucheoma you are just one of those fake online police men who think they are serving their superiors well, by kissin' ass and artificially boosting their post count with drivel and accusations. What's next , you'll start reporting anybodys posts cus all you do is kiss ass. lmao
Funny thing though, I know all the big dogs here.
 
T-Bone said:
LMAO stop shilling. Dermacrine is 1000 times better and isn't from a sh*t company.
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Or if you have a decent head on your shoulders you can always order the Raw supplements and go from there. I do think dermacrine will give RS a run for its money any day of the week
 
swollz said:
I had a similar question but I was wondering if taking clomid for trt and adding dhea good or bad?
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Clomid and HCG are often used trt. I have used both and personally prefer HCG. If you're already doing test injections then why not pick up some insulin needles and do a subcutaneous of HCG? Stimulates leydig cells hell of a lot better than Clomid. If you're worried about estrogen then I suppose Clomid may be a better option for you.
 
damage007 said:
Ucheoma you are just one of those fake online police men who think they are serving their superiors well, by kissin' ass and artificially boosting their post count with drivel and accusations. What's next , you'll start reporting anybodys posts cus all you do is kiss ass. lmao
Funny thing though, I know all the big dogs here.
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You know all the big dogs here??? Please clarify. Are you a sponsor on this board. Dont see ruthless supplements listed as a sponsor company??? Either way you come across as an egotist and im being civil here!
 
chemjr said:
Clomid and HCG are often used trt. I have used both and personally prefer HCG. If you're already doing test injections then why not pick up some insulin needles and do a subcutaneous of HCG? Stimulates leydig cells hell of a lot better than Clomid. If you're worried about estrogen then I suppose Clomid may be a better option for you.
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Unless you're wanting to have kids, HCG is not needed for TRT. The side effects of HCG outweigh the benefits.
 
I personally believe sides are dependent upon dosing. I've used low dose just to bring the boys back some and worked well. Also total and free t levels were higher so I'd guess it has more than just the baby making factor in there. Esp after adding dhea and some others into regime.
But in General, yes, it is a fertility drug, but also works similar to clomid as far as getting the loop going again. So saying it's just for kids is just a bit vague imo.
 
chemjr said:
I personally believe sides are dependent upon dosing. I've used low dose just to bring the boys back some and worked well. Also total and free t levels were higher so I'd guess it has more than just the baby making factor in there. Esp after adding dhea and some others into regime.
But in General, yes, it is a fertility drug, but also works similar to clomid as far as getting the loop going again. So saying it's just for kids is just a bit vague imo.
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While on TRT HCG causes issues with E2 which is tough to control just on test alone. Throwing HCG in the mix makes it worse. There's many guys on here that have cut HCG out of their protocol and stuck with test, preg, DHEA and vitamin d3. So yes while on TRT with test HCG is not needed unless your wanting to have kids. It's not my opinion, it's based on fact. If it works for you using it solo then great.
 
Actually I use it about every 6mo. Been on trt for 7+yrs now. And some of us don't have estro issues. I don't use an ai and don't need to, blood work agrees. I'm not sorry to have an opinion/experience. Ease up sir, we are all here to Help one another, not Correct them on their Personal experiences. What may work for one does Not for another, this is medicine- at its toughest I might add- where you'll find no two are alike. I just dont feel a person should wright it off bc of what common practice says. If i did I'd be screwed. Thx and take care.
 
chemjr said:
Actually I use it about every 6mo. Been on trt for 7+yrs now. And some of us don't have estro issues. I don't use an ai and don't need to, blood work agrees. I'm not sorry to have an opinion/experience. Ease up sir, we are all here to Help one another, not Correct them on their Personal experiences. What may work for one does Not for another, this is medicine- at its toughest I might add- where you'll find no two are alike. I just dont feel a person should wright it off bc of what common practice says. If i did I'd be screwed. Thx and take care.
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Me ease up? You're the one that's uptight. I believe I said in my last post if HCG was working for you then that's great. I wasn't trying to be hard to get along with. All I did was state a fact. It's also great you don't have to use an AI. Some guys do like myself. I tried everything known to man to control my E2 without an AI. But back to HCG....more times than not guys have a tough time with HCG and drop it. If it's working for you then great.
 
Ok, maybe I got the wrong impression. Just seemed to come on strong. And as for estrogen support, I personally make a very potent All Natural transdermal app if interested. I could send you a small sample bottle. Buddy of mine said it dried him out too much, lol. And idk if you have tried DIM in an appropriate dosage for guys like us, but has always worked wonders for me. Take care and if interested pm me.
 
lboston said:
For those that use DHEA with their TRT protocol, what does your dosing schedule look like?

Also, what effects do you notice?
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IM currently on 190mg test-c split into 2 does e3.5 days.

I use 25mg dhea 2 days on 1 day off.. it brought my Serum DHEA from likr 90 to 352.8 ug/dL

if my Serum DHEA SULFATE goes over 500 i get slight itch to my nips the night of injection so 300-400 is where i like it
 
That_TRT_Guy said:
IM currently on 190mg test-c split into 2 does e3.5 days.

I use 25mg dhea 2 days on 1 day off.. it brought my Serum DHEA from likr 90 to 352.8 ug/dL

if my Serum DHEA SULFATE goes over 500 i get slight itch to my nips the night of injection so 300-400 is where i like it
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Some DIM would most likely stop the nip itch, which is just some conversion imo, and then your dhea could be higher. And some zinc- helps w conversion as well.
Or high dose b6 + vit e + ashgwanda/maca. And you'll probably like the pro sexual "side effects" of the maca. But this second list is more a prolactin control, which w dhea shouldn't really be the issue, most likely conversion to estradiol. So some zinc may do trick alone and cheap as hell. DIM is 15$ for a 2mo supply and works Great for a natty "ai" so to speak. Best of luck.
 
No worries man. Thanks for the offer. No offense at all but I'm a little nervous about changing anything in my protocol at this point. I did try DIM along with zinc and I3C and it just wouldn't budge my E2. Stayed in the low 40's until I began arimidex. .25 mgs twice a week keeps be in the low 20's. Haven't had any issues with it at all. I will keep your transdermal in mind if something comes up. Again thanks for the offer!
 
sammpedd88 said:
No worries man. Thanks for the offer. No offense at all but I'm a little nervous about changing anything in my protocol at this point. I did try DIM along with zinc and I3C and it just wouldn't budge my E2. Stayed in the low 40's until I began arimidex. .25 mgs twice a week keeps be in the low 20's. Haven't had any issues with it at all. I will keep your transdermal in mind if something comes up. Again thanks for the offer!
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Hey, don't want you changing stuff if you don't have to. And I'm guessing you have a lot of aromatase enzyme floating around and that's why you need the adex. Surprised w DIM AND I3C as well as some zinc did nothing, that's crazy. I would figure some reduction at least. Oh well, just glad you found what works best for you. I just try to avoid scripts at all costs and does good for me and my clients so far. More power to ya and yes, holler anytime. Do prolactin ctrl as well if you ever need it. Also make a dermacrine-like preperation. Take care, A1 out
 
DIM shouldn't be expected to lower estrogen because it doesn't. It helps with the metabolism of good estrogen and lowering the bad metabolites. It is good for you, but certainly not an AI.
 
Sorry to change direction but is it a good idea to dose the TD DHEA mon,wed,Friday? Or seven days per week?
 
kisaj said:
DIM shouldn't be expected to lower estrogen because it doesn't. It helps with the metabolism of good estrogen and lowering the bad metabolites. It is good for you, but certainly not an AI.
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Agreed.
DIM increases the "good" estrogen metabolites that are known to be antioxidants, while reducing the levels of undesirable or "bad" estrogen metabolites which are not antioxidants and may contribute to cancer.

"Taking DIM not only promotes healthy estrogen metabolism, but it can also promote a more desirable action from testosterone."

Basically all I was saying. And if the guys working out, taking dim and I3C + zinc I'd figure there'd be Some reduction in his e2 levels, maybe even estradiol. No?

And 7,8 benzo should Def help as it is a natural ai. Also may boost test.

As for dhea, everyday imo. Think it all comes down to "seat of the pants" feel and what works for YOU. Every person is different and will respond differently.
 
Op, you can also get your test cyp compounded with dhea. I've seen it on the drug list for a popular compounding pharmacy. Im not sure if that would help you but its something to be aware of.
 
Invalid Link Removed might be even better than DIM, it actually hits aromatase expression.
Cancer Res. 2006 Jun 1;66(11):5960-7.
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Kijima I1, Phung S, Hur G, Kwok SL, Chen S.
Author information
Abstract
Aromatase is the enzyme that converts androgen to estrogen. It is expressed at higher levels in breast cancer tissues than normal breast tissues. Grape seed extract (GSE) contains high levels of procyanidin dimers that have been shown in our laboratory to be potent inhibitors of aromatase. In this study, GSE was found to inhibit aromatase activity in a dose-dependent manner and reduce androgen-dependent tumor growth in an aromatase-transfected MCF-7 (MCF-7aro) breast cancer xenograft model, agreeing with our previous findings. We have also examined the effect of GSE on aromatase expression. Reverse transcription-PCR experiments showed that treatment with 60 mug/mL of GSE suppressed the levels of exon I.3-, exon PII-, and exon I.6-containing aromatase mRNAs in MCF-7 and SK-BR-3 cells. The levels of exon I.1-containing mRNA, however, did not change with GSE treatment. Transient transfection experiments with luciferase-aromatase promoter I.3/II or I.4 reporter vectors showed the suppression of the promoter activity in a dose-dependent manner. The GSE treatment also led to the down-regulation of two transcription factors, cyclic AMP-responsive element binding protein-1 (CREB-1) and glucocorticoid receptor (GR). CREB-1 and GR are known to up-regulate aromatase gene expression through promoters I.3/II and I.4, respectively. We believe that these results are exciting in that they show GSE to be potentially useful in the prevention/treatment of hormone-dependent breast cancer through the inhibition of aromatase activity as well as its expression.
PMID: 16740737 [PubMed - indexed for MEDLINE] Free full text
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Sry, nevermind. Proceed.

And yes, GSE is awesome. Works very similar to letrone by black lion research* (I think that's the manufacturer?). Both work well. So well for me in fact that I had to stop (aching and popping joints).
 
I just added DHEA-S to my TRT supplement. Doc prescribed Oral 50mg/day that is mixed at a local compounding pharmacy. Supposed to be a lot better quality and somewhat time released compared to over the counter supps. Only been on it about a week, but so far I'm really liking the effects. Although I also added Cialas, so not sure if it is the DHEA or the Cilias or both, but it sure has helped with Energy and Bedroom Activities.
 
Cialis kicks in after 30 min. DHEA will kick in after a few weeks of taking it. How's your pregnenolone levels? BTW I love taking cialis too man! Makes for a great night with the wife!
 
damage007 said:
It is expensive, but worth it if you can afford it. Pills don't really cut it.
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There is literally 0 reason this product should cost that much. They're making some dumb margins on that. Dermacrine is a much better deal and very similar profile..... a much much much cheaper. That product probably costs easily under $20 a bottle to manufacture.
 
swollz said:
I had a similar question but I was wondering if taking clomid for trt and adding dhea good or bad?
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I would not take DHEA if you are concerned about HPTA suppression.

I took 100 mg/day for a couple months when I was trying to raise my E2 (I accidentally crashed it with A-dex), and while my DHEA went up quite a bit (229 to 737, in range 102-416), my testosterone went down (933 to 411, in range 348-1197).

maybe a smaller dose would have been less suppressive, but I suspect it would have still been somewhat negative in reference to my own production.
 
CatSnake said:
I would not take DHEA if you are concerned about HPTA suppression.

I took 100 mg/day for a coupe months when I was trying to raise my E2 (crashed it with A-dex), and while my DHEA went up quite a bit (229 to 737, in range 102-416), my testosterone went down (933 to 411, in range 348-1197).

maybe a smaller dose would have been less suppressive, but I suspect it would have still been somewhat negative in reference to my own production.
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100 mgs a day is way too much. Most guys on TRT take 25 mgs a day until they get their levels up, then take a maintenance dose. I get regular lbs and my Doc keeps a watch on my DHEA, pregnenolone, vitamin D among other things. DHEA and pregnenolone should be in every guy's protocol that is on TRT. Get regular labs to see how much you need to take.
 
sammpedd88 said:
100 mgs a day is way too much. Most guys on TRT take 25 mgs a day until they get their levels up, then take a maintenance dose. I get regular lbs and my Doc keeps a watch on my DHEA, pregnenolone, vitamin D among other things. DHEA and pregnenolone should be in every guy's protocol that is on TRT. Get regular labs to see how much you need to take.
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oh, I don't disagree about the TRT protocol. I was just responding to swollz, who was asking about using DHEA with clomid, which would be counterproductive, IMO.
 
sammpedd88 said:
My bad....I didn't see that. I agree!
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on a side note: the DHEA didn't really raise my E2 that much (from 5.5 to 6.2, in range 7.6-42.6).... and I was amazed how much it suppressed my testosterone. lots of people implied that it was pretty benign, but that's clearly not the case....
 
CatSnake said:
on a side note: the DHEA didn't really raise my E2 that much (from 5.5 to 6.2, in range 7.6-42.6).... and I was amazed how much it suppressed my testosterone. lots of people implied that it was pretty benign, but that's clearly not the case....
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I wonder if it suppressed it due to the high amount of DHEA you were taking? I've taken 25 mgs of DHEA and 75 mgs of pregnenolone everyday for 3 1/2 years and my dr dialed back the amount of my injections of test. I'm down to 50 mgs twice a week of test because my free T was through the roof. Weird how things can work differently from person to person.
 
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