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DHEA DOSE

Have always heard DHEA should be used in a transdermal. Oral DHEA has a very low bioavailability??? Anyone confirm this???
 
For most people, it's going to be pretty useless. If you're getting up there in age, it could be beneficial.

Even if you were to try to use it as a test base on cycle, you're better off using 4-dhea for that purpose.
 
kissdadookie said:
For most people, it's going to be pretty useless. If you're getting up there in age, it could be beneficial.

Even if you were to try to use it as a test base on cycle, you're better off using 4-dhea for that purpose.
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This. Very little is converted to test. If you are deficient, it is great for energy and mood, but other than that you would not get much out of it.
 
kisaj said:
This. Very little is converted to test. If you are deficient, it is great for energy and mood, but other than that you would not get much out of it.
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I was tested and am deficient. However, i also read the oral doses are not very effective and transdermal is the way to go. I continue to use oral, and notice slight change in mood, bit happier.. But am considering trans... thanks about the 4-dhea and link
 
kisaj said:
This. Very little is converted to test. If you are deficient, it is great for energy and mood, but other than that you would not get much out of it.
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I second what kisaj says. I did 5 weeks of ams 1-andro and 4 ad combined. Nothing. The benefits i did see were due to upping my caloric intake. And i significantly upped the dose of 1 andro from the bottle recommendation. Nothing strength wise that couldnt be attributed to calorie increase. No suppression, nothing. Folli, viron , inhibit e are on deck. Well see
 
pcarzola said:
I second what kisaj says. I did 5 weeks of ams 1-andro and 4 ad combined. Nothing. The benefits i did see were due to upping my caloric intake. And i significantly upped the dose of 1 andro from the bottle recommendation. Nothing strength wise that couldnt be attributed to calorie increase. No suppression, nothing. Folli, viron , inhibit e are on deck. Well see
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I used 1-andro rx and 4-andro rx (300 1-dhea, 200 4-dhea) from IML. Mild cycle and good strength gains along with recomp.
 
kisaj said:
That would be a flawed study.
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Liu, T., et al. Effect of Acute DHEA Administration on Free Testosterone in Middle-Aged and Young Men Following High-Intensity Interval Training. European Journal of Applied Physiology. 2013. Published Ahead of Print.

The study showed that at baseline, free testosterone, which is the form that is able to interact with tissue to build muscle, was 75 percent lower in the middle-aged men (49-year-olds) than in the young (21-year-olds) men. Giving both groups one 50 mg dose of DHEA raised free testosterone levels significantly before the workout (from 2.76 pg/ml to 9.99 pg/ml in the older men, and 9.22 pg/ml to 19.4 pg/ml in the younger men). The free T to cortisol ratio was also much more favorable before the workout in both groups, indicating that DHEA is effective for acutely raising T.

Then, after a high-intensity interval workout free testosterone stayed the same, whereas total testosterone dropped in both groups. Researchers think the mechanism via which free T stayed elevated but total testosterone dropped has to do with DHEA decreasing the amount of sex-hormone binding globulin present, which binds to T and makes it unavailable for tissue interaction. So, lower SHGB means less T is bound to it and more is free to build muscle.
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I believe the intervention was too short to note any specific body composition changes, however I'd try this for 12 weeks to see. Then again, if we take trained individuals between 8-10% bf (DEXA scanned) and put them through a hypetrophic training regimen, who knows if it's the low bf %, training or supplementation that would yield the gains.
 
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