I like spreading out the dosage through-out the day so I taking it in at least 3 different times. Creatine usually makes me hold a lot of water under the skin giving me a 'puffy' look. But since I spread out the dose, I don't notice this problem anymore (given that I drink enough water).
Your body can only use so much creatine. So start at 5g and then move to 10g to see how it treats you. You can even more up to the 15-20g range like lifting4fun and see how it treats you. And don't worry, creatine is safe. Just make sure you are drinking enough water to avoid cramps.