Clen & Thyroid Function

[WeightShift]

I've run Clen in the past and absolutely love the stuff. I've generally done 3 to 4 weeks supplementing with taurine and benadryl.

With that said, it is thought that clen interferes with T4's conversion to T3 which impairs your thyroid's normal functioning (hence the Clen/T3 cycle). Do any of you see it necessary to run any sort of PCT with thyroid normalization in mind?

From my understanding, the thyroid is extremely resilient, but I'd just like to hear other's opinions.

 

[iceman5005]

youre wrong, clen got nothing to do with hormones!!!!
Its beta-2 sympathomimetic, witch is a anti-catabolic aswell!!!
u can combine it of course with thyroids for bether burning,but thats another story...

 

[WeightShift]

Thanks for the response. I'm aware of the pathways that it uses (ie: mitochondria stimulation), but here is the theory behind it.

Your body warms up due to mitochondrial hyperactivity. As part of the negative feedback loop, your thyroid no longer needs to worry about its own job of aiding in homeostasis as doing so may lead to overheating. Instead, it easy signals for less enzyme release for T4 conversion or simply releases less T4.

Anybody else have thoughts?

 

[russy_russ]

Thanks for the response. I'm aware of the pathways that it uses (ie: mitochondria stimulation), but here is the theory behind it.

Your body warms up due to mitochondrial hyperactivity. As part of the negative feedback loop, your thyroid no longer needs to worry about its own job of aiding in homeostasis as doing so may lead to overheating. Instead, it easy signals for less enzyme release for T4 conversion or simply releases less T4.

Anybody else have thoughts?

I believe the hydrolization of T4 to T3 would be slowed down from the feedback loop.

 

[WeightShift]

So as soon as the clen clears from your system, T4 conversion should quickly normalize?

 

[russy_russ]

As your body becomes closer to its homeostatic ranges, T4 - T3 conversion should normalize.