I didn't notice a thing! I'm 40 so my joints ache some. The cissus works wonders man, use it! If I forget to take it my knees and elbows are barking at me me all day. Ill take it when I get home and get relief in a couple hours. This stuff is waaaayyyyyy better than Gluc/ condroiton/MSN!!!
I dont think it hurt my gains at all, 'couse Im just finnishing my first cycle so I have nothing to compare to.