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Calcium and magnesium, but not dairy intake, linked with increased insulin sensitivity
A report published in the September, 2006 issue of the American Journal of Epidemiology revealed an association between increased insulin sensitivity and greater intake of calcium and magnesium. Reduced insulin sensitivity occurs in metabolic syndrome and diabetes type 2 when individuals produce adequate or even excessive insulin, but have become resistant to its effects. Although previous studies have indicated an association between dairy intake and insulin sensitivity, the current study failed to confirm this.
Researchers at the University of South Carolina in Columbia evaluated data from 1,036 men and women without diabetes enrolled in the Insulin Resistance Atherosclerosis Study. Food frequency interviews including dietary supplement doses were conducted at the beginning of the study. Insulin sensitivity was measured with an intravenous glucose tolerance test upon enrollment and after five years of follow-up.
The average daily calcium intake of the participants was 970 milligrams, and the average intake of magnesium was 403 milligrams. Seventeen percent of the participants reported using calcium supplements, and 5 percent used magnesium supplements. After adjustment for demographic factors, dairy intake was not found to be associated with insulin sensitivity, however, positive and independent associations of calcium and magnesium with insulin sensitivity were demonstrated. Magnesium appeared to increase insulin sensitivity up to a daily intake of 325 milligrams, suggesting that more than this amount may not be of further benefit for this concern, although higher doses of magnesium could be beneficial for other purposes.
Magnesium may play a role in glucose homeostasis and insulin action, and calcium supplementation has been shown to reduce fasting insulin and increase insulin sensitivity in one clinical trial of nondiabetics. The authors observe that it is important to determine the optimal intake of these minerals, because excessive doses could decrease the absorption of other minerals.
A report published in the September, 2006 issue of the American Journal of Epidemiology revealed an association between increased insulin sensitivity and greater intake of calcium and magnesium. Reduced insulin sensitivity occurs in metabolic syndrome and diabetes type 2 when individuals produce adequate or even excessive insulin, but have become resistant to its effects. Although previous studies have indicated an association between dairy intake and insulin sensitivity, the current study failed to confirm this.
Researchers at the University of South Carolina in Columbia evaluated data from 1,036 men and women without diabetes enrolled in the Insulin Resistance Atherosclerosis Study. Food frequency interviews including dietary supplement doses were conducted at the beginning of the study. Insulin sensitivity was measured with an intravenous glucose tolerance test upon enrollment and after five years of follow-up.
The average daily calcium intake of the participants was 970 milligrams, and the average intake of magnesium was 403 milligrams. Seventeen percent of the participants reported using calcium supplements, and 5 percent used magnesium supplements. After adjustment for demographic factors, dairy intake was not found to be associated with insulin sensitivity, however, positive and independent associations of calcium and magnesium with insulin sensitivity were demonstrated. Magnesium appeared to increase insulin sensitivity up to a daily intake of 325 milligrams, suggesting that more than this amount may not be of further benefit for this concern, although higher doses of magnesium could be beneficial for other purposes.
Magnesium may play a role in glucose homeostasis and insulin action, and calcium supplementation has been shown to reduce fasting insulin and increase insulin sensitivity in one clinical trial of nondiabetics. The authors observe that it is important to determine the optimal intake of these minerals, because excessive doses could decrease the absorption of other minerals.
