He's DHEA levels are a bit low. Not low enough for his doctor to prescribe him something but he wants to prevent any further decline. He's been having some brain fog, joint pain, lack of concentration, lack of libido and just wants a boost tbf... Everything that Dermacrine is supposed to support/help with.
Most of the data on dhea supplementation in men shows it will have No Significant impact on TT or E2 levels; it is unlikely it will be impacting LH or FSH either. Interestingly, the data on women is much more clear: dhea supplementation has Significant impact on TT levels but
no impact on LH, FSH, or lipids.
The only data Ive seen on dhea supplementation Significantly impacting men is a case study of two 70 year olds who ingested 400mg.
As per the LEF site, it would seem that
physiological doses of dhea that restore normal serum levels will not impact TT nor the hpta; it is only, possibly,
supraphysiological doses that might.
He's got no issues or reservations about taking SERM's if he needed too, but they can present their own problems so would rather not go overkill if he doesn't have too.
I suppose a low dose of about 3-4 pumps per day for a month or two shouldn't cause much suppression or E related sides.
And I have a box full of Pharma Grade AI's and SERM's that I'd dip into for him if issues do arise. But again, I'd rather him not have too take them.
The way I see it he has pretty much three post-dhea options:
1) use a SERM. The impact of this will largely depend on his pre-SERM hormonal environment. Generally, the only real "negative" I could see going this route is a level, likely E2, being raised to some undesirable degree, SERM-dependant. I personally find the idea of a SERM being "overkill" an unwarranted knee-jerk reaction. To be absolutely clear: claiming something to be "overkill" also presumes some kind of action
is warranted. If a SERM is overkill, what is Goldilocks "just right"?
2) use an OTC test booster. This will tend to have minimal impact on any LH or FSH activity; if a SERM is overkill, a test booster is underkill
if hpta function is your concern. If youre restoring physiological levels of dhea, how exactly is an OTC test booster in any way relevant post-treatment?
3) do nothing. Or, spend the $$ on pre- and post-treatment bloods that demonstrate impact on DHEA/S, TT, E2, LH, FSH, lipids. Thatd be my own personal approach.