I'm not going to claim to be 100% accurate on this, but from my understanding it works fine, from the compounding specialist point of view it's not optimal as there looking into the best conditions. I'm pretty sure they also factor in how you can't control dose and dosing schedule the same way you could if the products were separate. I've used both products for multiple sources separate many times and since I've been able to get the combos I've only used it as a combo. I haven't noticed any difference. Now that's not to say that one or the other could be doing all the work, I guess I have no way of knowing that. One thing, important thing to add, if there was an issue with the pH being off and one of the compounds was to denature, it would reconstitute cloudy instead of clear. If it reconstitute and stays clear the products have not denatured so they're good. Now to be fair I have absolutely reconstituted a bottle before that looked a tiny bit cloudy, but at the same time that one had been sitting in my top drawer for months, like maybe even a year. Every bottle might be slightly cloudy as you're rolling it around but once it settles and sits in the fridge for a little while the bottle should look clear, like water.
I'm rambling but basically if you reconstitute something and it doesn't turn cloudy you should be gtg