Youre in a surplus 5.5 days out of 7 and you seriously wonder why youre having trouble losing weight? Jesus bro...
This. I don't have any comments on hormonal or more fringe products for fat loss.
Maybe goes against what some people will claim, but I also think lots of extended fasting for fat loss just doesn't sound beneficial. Especially if maintaining lean mass is an issue I am not sold on that being the most optimal approach (eating surplus then just trying to fast to lose sounds also mentally questionable to me from a psychosocial approach as well).
I don't want to get too complicated or delve too deep, but if you are having issues both gaining and losing there are probably tweaks that need to be made (which can be hard to fully iron out just online even with the good help of lots of guys on here).
I'd be willing to bet that if you really have issues gaining (and we go under the assumption that it isn't diet related) that if you can't put muscle on without fat there is an issue with the type of training or how you are training. Again that is something in and of itself that could take a while to dissect and sometimes on forums we just glance past it (I am guilty as well) with being like oh you train three days per week and do these exercises it sounds ok. The intent and the technique may be off to not be providing the proper stimulus, the volume of work could be too low, etc.
Then there may still be some diet stuff still as well. I know I can feel myself going on a long rant/tangent so if you are still with me I apologize for my inability to be brief and know I don't type this to try and pile on, I legitimately want to help. I'd argue even if we feel your macros are correct maybe there are some underlying issues with needing more micros, vegetables, and fruits to help fuel much lower base processes that may be detrimental (partly feeding into what you measure as hormonal issues) and making it hard to eat in a deficit.
I'll end with saying, maybe controversially, it isn't always about looking for the optimal way to cut the calories out (fasting being about the furthest end we can go on that spectrum), but that recently I've been considering the success I see with some in an idea or fashion of trying to prime to body to burn and eat more to still lose. I am not saying we are looking to disregard the thermodynamics of intake/outtake, but that with a system that has been in constant surplus for most of its life the internal machinery just may not be working optimally. If we can get expenditure amounts up (both through structured training and finding an increased and sustainable NEAT boost), we can get the body to eat more as well (while still being in a deficit hopefully, if not know then hopefully down the road to make losing easier), so that we are pushing and pulling more "through the system" therefore making a more efficient system so that weight loss is more readily attainable and maintained.
I probably didn't type that the way I'd prefer and sure maybe I'll get some disagreement, but going off similar ideas of energy flux and ideas similar to this study finding low energy flux was better at predicting weight loss regain:
https://academic.oup.com/ajcn/article/103/6/1389/4637455
Sorry for the long post, I know it sucks, dieting sucks, our world makes it near impossible, but know even if it feels like you are beating your head against the wall that most of us just want to help and we understand (to different extents) the struggle. Good luck!