Found this quote from PA regarding 6-oxo....
"Contrary to testosterone levels, changes in estradiol levels were slight but not statistically significant. The explanation for this is simple. 6-OXO acts to inhibit the aromatase enzyme and block the conversion of testosterone to estradiol. A consequence of this is a signal from the brain to increase production of testosterone to compensate for the blocked estradiol production. As testosterone levels increase, so do estradiol levels since more substrate has now become available for the aromatase enzyme. Basically, what has occurred is the establishment of a new baseline level of testosterone to maintain the body's normal levels of estradiol.
This sort of hormonal response is very desirable. It is probably not healthy to lower estradiol levels below the physiologically normal range, so if we are able to raise testosterone without lowering estradiol this is great! Mind you, we don't know what will happen if doses over 600mg a day are ingested. It could be that at higher dosages the aromatase inhibition becomes too great for increased testosterone production to overcome. In that case, a more dramatic lowering of estradiol will be seen. This is something that we probably want to avoid, at least for any longer than the short term."
For someone like me who wants to eliminate the excess estradiol in my system that I got from the last rebound, this is not ideal LOL.
Hence me wanting seeking out a new AI like Aromasin.