Guest viewing is limited

bad review given of oxyelite pro on website

shinivan said:
for years had the thinking that big appetite meant fast metabolism
Click to expand...
ahaa, don't know that I'd ever agree with that one.
there are a lot of obese ppl out there with hella big appetites, but I don't think their metabolism is humming along quite efficiently. ;)
but i think i read somewhere that loss of appetite when on an effective fat burner means that your fat burner is actually doing its job as is releasing energy or calories from fat deposits thus why you are in less hunger due to having fatty acids flowing on the bloodstream from the reserves being freed.
Click to expand...
now this one makes sense. :)
 
DAdams91982 said:
You do know that Raowolscine and regular Yohimbine are two VERY different things right? alpha-Y is extremely different from what you are thinking of.

But the science still supports aY as a viable ingredient.
Click to expand...

thought I'd expand a bit on the difference here, since I have the time now and access to the write-up:

Rauwolfia Canescens (Rauwolscine)

This particular compound has been shown to block off & deactivate the Alpha-2 receptor!

It's related to yohimbine, a compound which is often included in various fat loss formulas because of its ability to antagonize alpha 2-adrenoceptors, allowing lipolysis itself, while also allowing lipolysis to continue from beta adrenoceptor agonism as well (11,12).

Here's the problem: While antagonizing alpha 2-adrenoceptors is great, yohimbine unfortunately also does the same for alpha 1-adrenoceptors – and this can actually hinder lipolysis (13).

So, on the other hand, while yohimbine helps to improve lipolysis by antagonizing alpha 2-adrenoceptors, it may also prevent lipolysis from occurring by antagonizing alpha 1-adrenoceptors...

Kind of defeats the purpose, huh? It's like robbing Peter to Pay Paul...

The end result is only a mediocre or small effect upon fat loss, or no detectable fat loss at all, which is what has been demonstrated in the literature with yohimbine supplementation (14-17).

Rauwolscine on the other hand, is just as potent at antagonizing alpha 2-adrenoceptors as yohimbine, yet it is 50 times less potent at alpha 1-adrenoceptors (18), making it much more selective and much less likely to reduce lipolysis by inhibiting alpha 1-adrenoceptor activity when compared to yohimbine.

Rauwolscine is clearly the better choice.

Last, beware of those products which contain the hydroxylated derivatives of yohimbine (e.g., 10-OH-yohimbine and 11-OH-yohimbine). They may look different but the truth is that they are no more effective than yohimbine (19).

This is simply a marketing gimmick designed to get the consumer to believe they are getting something truly unique and more effective.
Click to expand...

again, detailing the effects of raised norepinephrine levels (from substances like caffeine), we have this..

This increased norepinephrine again contributes to increasing UCP-1 activity in BAT, unfortunately, it also ends up activating alpha 2-adrenoceptors...

...And by doing this, it actually inhibits some of the potential lipolytic and thermogenic activity of norepinephrine by inhibiting adenylyl cyclase (i.e., the enzyme which allows for cyclic adenosine monophosphate or cAMP formation and what ultimately leads to lipolysis) activity (25,28).

This is where rauwolscine comes in to play as it is an alpha 2-adrenoceptor antagonist. It prevents this inhibition of adenylyl cyclase and thus can potentially lead to a further increase in cAMP, lipolysis and thermogenesis via UCP-1...

Again, this is where rauwolscine shows its superiority to yohimbine...

You see, the alpha 1-adrenoceptor is also activated by norepinephrine and it also contributes to increased UCP-1 activity and subsequent thermogenesis (28,29,31,32).

At least one partial mechanism for how the alpha 1-adrenoceptor exerts such an effect is by increasing the conversion of T4 to T3 within BAT, which in turn increases UCP-1 expression.

...So, although yohimbine has some beneficial effect upon fat loss, it's this blocking of activity at the alpha 1-adrenoceptor that becomes its downfall. Rauwolscine is 50 times less potent at antagonizing the alpha 1-adrenoceptor and thus makes a much better agent to use for fat loss.
Click to expand...
 
hardknock said:
..
Yeah but they will spring up in 6 months with another scam. These guys make off with hundreds of thousands, if not, millions of dollars. That thing called the interwebz is one powerful mofo...more seductive than sex.
Click to expand...

Actually new regulation came in Jan this year which allows the FTC to come down on these f**ckers hard which included being blacklisted from getting a merch account among more serious measures.

Should be an interesting year once the **** hits the fan...
 
Summer are brutal here in Bama it's no joke

hardknock said:
..
while in alabama it was 60 tuesday
Winters aren't so bad, coldest it has been was 15F which was brutal...warmest its been this winter was 70F. lol

Summers are murder though, wet sticky heat @ 100+. You cannot even breathe outside without an oxygen mask.
Click to expand...
 
You must log in or register to reply here.
Back
Top