Article: Optimal Melatonin Dosing
- Thread starter The Press
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BCseacow83
Well-known member
Many times I have customers come in looking for a sleep aid. I always ask have they tried melatonin as it is relatively safe, studied in humans, and keeps with the bioidentical nature of hormones in the body. The usual response is, "It did nothing for me." Since I want them to try to get the most out of a product they have already purchased I explain to them the HUGE variance in dosing available on the market. First I suggest they take what ever they have, usually 3mg tabs or caps and cut the dose in half(or empty out half the capsule.) If this does not work I then suggest taking it in the late afternoon when the sun starts to go down. IMO it's not like our biological clock goes from fully awake to Oh it dark crank out the melatonin. Melatonin will increase the darker it gets but to be more in synch with what would normally happen having levels gradually increase as the sunlight decreases makes sense.
I have also seen a study that showed that those that dosed in the later afternoon, say 5or6 pm with the goal of sleep at 10pm had better results than the 30 minutes prebed recommended on so many bottles. I know personally I get an effective response from breaking a 1mg SL tab into about fourths. Also works well in the middle of the night when you need to get back to sleep but a full dose may leave you groggy in the morning.
All things being tried if they still get no response to Meatonin then I suggest they look into alternative. Sleep is a trick bugger and what works very well for one individual can do nothing for another. I have had those that melatonin stimulated them so go figure. Also I can't find the paper right now but I read about the hypothesis that too high of a dose down regulates receptors and can have the opposite effect for some.
OT I have had customer who when they came to see me were taking 40MG a day in a desperate attempt to sleep.
I have also seen a study that showed that those that dosed in the later afternoon, say 5or6 pm with the goal of sleep at 10pm had better results than the 30 minutes prebed recommended on so many bottles. I know personally I get an effective response from breaking a 1mg SL tab into about fourths. Also works well in the middle of the night when you need to get back to sleep but a full dose may leave you groggy in the morning.
All things being tried if they still get no response to Meatonin then I suggest they look into alternative. Sleep is a trick bugger and what works very well for one individual can do nothing for another. I have had those that melatonin stimulated them so go figure. Also I can't find the paper right now but I read about the hypothesis that too high of a dose down regulates receptors and can have the opposite effect for some.
OT I have had customer who when they came to see me were taking 40MG a day in a desperate attempt to sleep.
Red Weight
New member
We can get 3 mg and 5 mg in Europa. So the ban must be banned 
Personally I only sleep when take 6 mg about 60 minutes before bed time. Less doesn't do anything and more keeps me awake and makes me dream like crazy when I finally fall a sleep.
Personally I only sleep when take 6 mg about 60 minutes before bed time. Less doesn't do anything and more keeps me awake and makes me dream like crazy when I finally fall a sleep.kissdadookie
Well-known member
This is one ingredient that is essentially being misused. Melatonin is really to be used to help knock your circadian rhythm back. It's not really to be used as a sedative, which I see most people using it as.