Anyone feeling better on less frequent injections (e7d vs e3.5d and less) ?

DonaldPump2020

New member
So I experimented a lot with different trt protocols.
First started daily gel. Then did e3.5d subq at 100mg, 120mg, 150mg. Also did ED 20mg Subq. Felt the worst on ed shots, even though my shbg was low pre-trt (23)

On e3.5d 60mg subq I had a total T of 630ng/dl on through and an E2 (NON-sensitive., cant get sensitive here) of 51.

I felt way worse than on gel. Well once I tested at 650 ng/dl 5hrs after gel application (and levels drop off even further every hour) and yet i felt way better than on injections with the same level.

I guessed i felt better on gel cause of daily appl. since I had low shbg, so i tried ED injections (ed 20mg subq). felt the WORST. felt almost exactly like PRE-TRT. Horrible low e2 symptoms.

Switched to e3.5d, felt better but still felt worse than gel and definitely suboptimal.
I still have what I think are low E2 symptoms. Im dried up, kinda dry skin, dry eyes when sleeping/waking up, dehydrated after waking up, anhedonia, obsessive thoughts, no libido, no erections except at sleep sometimes.

So somehow, I GUESS i felt better on Gel cause of higher E2 conversion. There were moments on gel where I had oily skin, acne, a red flushed face, itchy nips. At this moments I felt the best mentally wise, which is high e2, isnt it.

So today i finished 6 weeks of e3.5d 75mg Intramuscular. Still dont feel good, so I wanna try out E7D to get more aromatase conversion to e2 at once.

I know everyones saying more frequent is better, especially for low SHBG guys, but unfortunately it doesnt seem to work?

Anyone feels better on less frequent injections? If i notice its working better but leaves me crashing at day 5-7 I can go on to E5D
 
Gels tend to promote more DHT conversion than injections so that might be what your experiences in the differences. I don't absorb my TRT for crap sub-q and do shallow IM with insulin needles.
 
since less frequent larger shots should also get more conversion to DHT that could also fix the problem if it is indeed low dht.
but my symptoms do more look like low e2, but thats just a guess
 
DonaldPump2020 said:
since less frequent larger shots should also get more conversion to DHT that could also fix the problem if it is indeed low dht.
but my symptoms do more look like low e2, but thats just a guess
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You need blood work to figure this out until you learn enough about your body to go by feel. I've been on TRT a long time and still get it wrong sometimes without blood work.,
 
Twice a week enanthate feel great 160mg a week but erections are not the greatest...Daily at 20mg of cyp after awhile get extreme fatigue..Eod 32mg of enanthate everything is fine but libido suffers..eod cyp 40mg everything is fine but libido suffers and breakouts..might try 3xs a week at 52mg next of enanthate for a few months see how that goes..still doing twice a week of enanthate like to give it another 8 weeks..I stay on protocols for 12 to 16 weeks before making any adjustments
 
ohiostate2827 said:
Twice a week enanthate feel great 160mg a week but erections are not the greatest...Daily at 20mg of cyp after awhile get extreme fatigue..Eod 32mg of enanthate everything is fine but libido suffers..eod cyp 40mg everything is fine but libido suffers and breakouts..might try 3xs a week at 52mg next of enanthate for a few months see how that goes..still doing twice a week of enanthate like to give it another 8 weeks..I stay on protocols for 12 to 16 weeks before making any adjustments
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so do you think me having injected 150mg all at once f*ed up my whole process of dialing in, resetting the whole thing?
I meant it cant make any sense.
Yes I know many benefits of TRT appear way later than 6 weeks, and i know about the talk that hormonal changes take a long time to influence cell signalling and whatever, but as I did injections (for multiple MONTHS now.) I applied some gel i had left over to see if my current problems are related to hormones.

and YES. most of the time just 1 gel application fixed all my problems overnight. So i cant see why the same hormone from gel fixes all my problems in a day while it takes 4 months on injections?

only difference i see could be E2.

I cant see how me changing doses too early, after 6 weeks, makes E2 disappear from my body leaving me with low e2 symptoms? it doesnt make any sense lol
 
DonaldPump2020 said:
so do you think me having injected 150mg all at once f*ed up my whole process of dialing in, resetting the whole thing?
I meant it cant make any sense.
Yes I know many benefits of TRT appear way later than 6 weeks, and i know about the talk that hormonal changes take a long time to influence cell signalling and whatever, but as I did injections (for multiple MONTHS now.) I applied some gel i had left over to see if my current problems are related to hormones.

and YES. most of the time just 1 gel application fixed all my problems overnight. So i cant see why the same hormone from gel fixes all my problems in a day while it takes 4 months on injections?

only difference i see could be E2.

I cant see how me changing doses too early, after 6 weeks, makes E2 disappear from my body leaving me with low e2 symptoms? it doesnt make any sense lol
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Why did you quit the gel if you were feeling alright..how often are you changing protocols?.good 8 weeks before changing things..I have low shbg but 2xs a week have been best except weak erections which may resolve in the next month or so..idk why your e2 is moving around like it is...your body just metabolize different
 
ohiostate2827 said:
Why did you quit the gel if you were feeling alright..how often are you changing protocols?.good 8 weeks before changing things..I have low shbg but 2xs a week have been best except weak erections which may resolve in the next month or so..idk why your e2 is moving around like it is...your body just metabolize different
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Gels worked amazing at start but at some time they kinda stopped working, maybe due to skin becoming less absorbant.
It was also a pain in the a** to apply everyday cause it would take 40 minutes to fully dry.

Its also so unreliable. Someday your body absorbs less, someday you scrub something off accidentally, some day you sweat more, often you couldnt shower cause you would need to leave the gel on the skin for 5 hours before washing. It was too much of a hassle.

Longest i was on injections steadily was 8 weeks 20mg everyday subq. I did everyday cause i thought everyday gel worked best in the past, maybe due to low shbg (23 pre-trt). but i felt the same as pre-trt, minus panic attacks. could have ended in suicide, it was so bad. I cant see how i would magically feel better with continueing it for some more weeks.

When I was using gel and at some time had high e2 symptoms i would literally feel the BEST. really content and calm
 
DonaldPump2020 said:
Gels worked amazing at start but at some time they kinda stopped working, maybe due to skin becoming less absorbant.
It was also a pain in the a** to apply everyday cause it would take 40 minutes to fully dry.

Its also so unreliable. Someday your body absorbs less, someday you scrub something off accidentally, some day you sweat more, often you couldnt shower cause you would need to leave the gel on the skin for 5 hours before washing. It was too much of a hassle.

Longest i was on injections steadily was 8 weeks 20mg everyday subq. I did everyday cause i thought everyday gel worked best in the past, maybe due to low shbg (23 pre-trt). but i felt the same as pre-trt, minus panic attacks. could have ended in suicide, it was so bad. I cant see how i would magically feel better with continueing it for some more weeks.

When I was using gel and at some time had high e2 symptoms i would literally feel the BEST. really content and calm
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Could try scrotum cream..alot ppl use empowers cream with success
 
I do 1 shot of 200mg a week, feel good, high DHT, slightly high E. To me it’s annoying to do more shots than that. Everyday?! F that.
 
BBiceps said:
I do 1 shot of 200mg a week, feel good, high DHT, slightly high E. To me it’s annoying to do more shots than that. Everyday?! F that.
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BBiceps said:
I do 1 shot of 200mg a week, feel good, high DHT, slightly high E. To me it’s annoying to do more shots than that. Everyday?! F that.
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How high is slightly high E?..curious what your total and free test is at once a week..
 
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BBiceps said:
What do you mean? I agree it’s a high total test but 1 shot will give a higher peak than 2 shots for an example.
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You didn't wait just before your next injection to get labs?.. your shbg high?... my shbg is low I have to inject 3xs per week to keep testosterone lvls from fluctuating..
 
ohiostate2827 said:
You didn't wait just before your next injection to get labs?.. your shbg high?... my shbg is low I have to inject 3xs per week to keep testosterone lvls from fluctuating..
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No, that was 3 days after injection, 8 days after injection in 980. My shbg is in the middle on both. My DHT is high. I do not “feel” any difference in performance or mood.
 
BBiceps said:
No, that was 3 days after injection, 8 days after injection in 980. My shbg is in the middle on both. My DHT is high. I do not “feel” any difference in performance or mood.
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Whatever works..my shbg varies 16 to 19..burn through test too fast for once a week
 

Boron can help with the free test, I noticed a increase when I’m taking it. Have you tried 1 or 2 times a week? After I’m done with my blast I will try 2 times, I’m not sensitive to test so “feel wise” I don’t think it’s a difference but maybe I can keep my E lower if I inject 2x week.
 
BBiceps said:
Boron can help with the free test, I noticed a increase when I’m taking it. Have you tried 1 or 2 times a week? After I’m done with my blast I will try 2 times, I’m not sensitive to test so “feel wise” I don’t think it’s a difference but maybe I can keep my E lower if I inject 2x week.
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2xs a week injections 80mg on Monday 80mg on Thursday ..TT 800S..FT 26..E2 39..I felt pretty good on twice a week wanting to get e2 down to 30 is my goal without an AI..erection quality is best when e2 is lower 30s or mid 20s
 
I couldn't imagine pinning every day to mimic natural test secretion.
At that point I will just drop the test and go back.

Every 7 days 200 and im golden across the board with sides. Puts me in the low cycle Range with test tho. Currently on a blast and loving life
 
Quest said:
I couldn't imagine pinning every day to mimic natural test secretion.
At that point I will just drop the test and go back.

Every 7 days 200 and im golden across the board with sides. Puts me in the low cycle Range with test tho. Currently on a blast and loving life
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Its not bad doing more frequent injections..I use half inch 29g diabetic needle rotate left and right side delts...
 
ohiostate2827 said:
Its not bad doing more frequent injections..I use half inch 29g diabetic needle rotate left and right side delts...
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The “sticking part” does not bother me, not even with a 23g needle, it’s the whole process that’s annoying to me. I’m on a blast now and pinning 3x week and it’s sooo annoying but it’s too much volume to do in 2 so got to do it... 🤷🏻‍♂️

But if you can do it and it works for you it’s all good, keep doing what makes you happy.
 
LaserGoPewPew said:
Where do you want your SHBG to be? What levels across the board make you feel your best? I may try boron push mine down a bit to see how if that improves libido etc ... labs below are 5 months after stopping TRT

  • SHBG 39 (10-50)
  • Test, total 321 (250-1100)
  • T3, free 3.6 (2.3 - 4.2)
  • Test, free 37.8 (35-155)
  • DHEA sulfate 318 (70-495)
  • Estradiol 22 (under 39)
  • LH: 5.0 (1.5 - 9.3)
  • FSH: 2.9 (1.6-8.0)
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Why did you stop trt?
 
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