I'd save the guggul supps for after the Tri-Max cycle. Since Tri-Max seems to kill natty t3 production pretty severely (although I didn't "feel" it in my case, but I didn't have a test done), using guggul is probably good to help spur the thyroid back to normal function. You'll have so much T3 flowing through you while on Tri-Max I almost think the guggul while on won't really help as your thyroid will have already gotten the signal to chill out because there is so much T3.