it may depend on the individual also. While some 17-aa's are "harsher" than others, so are some people more sensitive to this, so it's hard to give you much other than:
1. yes, it will more than likely have a negative effect on your lipid profile and BP
2. the severity will depend on your unique reaction, dosage, and length taken, among other factors
3. this is a risk you take with AS no matter what you take. Be prepared (supps, diet, etc) and plan a safe cycle