Nektar
New member
.......Drum roll.................its not nektar but Bee venom:
'The bee venom peptide melittin stimulated a profound AA release response in the cells and the concomitant synthesis of both cyclooxygenase (PGF2 alpha, PGE2 and PGD2) and lipoxygenase (5-,12-,15-HETE and possibly 5-,12-diHETE) metabolites of AA.'
An extract called 'Chaparral' is the most potent lipoxygenase inhibiter i know of that selectively inhibits while sparing the COX2 pathway. u can buy for under $10 to potentiate PGF2a release.
'Exposure to the bee venom peptide melittin, to increase PLA(2) substrate availability, potentiated arachidonic acid release'
'Melittin stimulates ... hydrolysis of phospholipids by phospholipase A2 to release arachidonic acid (AA).'
'melittin stimulates the synthesis of PGF-2 alpha and PGI-2 (measured as 6-keto-PGF-1 alpha) in guinea-pig uterus by mechanisms which are calcium dependent.'
In google books search for 'Mechanisms of Physical and Emotional Stress' and pg 94 will summarise most of this.
Anyone tried this sup on their Arachidonic acid cycle to release more PGs? looks pretty interesting
(U can see the studies by searching for the quotes)
'The bee venom peptide melittin stimulated a profound AA release response in the cells and the concomitant synthesis of both cyclooxygenase (PGF2 alpha, PGE2 and PGD2) and lipoxygenase (5-,12-,15-HETE and possibly 5-,12-diHETE) metabolites of AA.'
An extract called 'Chaparral' is the most potent lipoxygenase inhibiter i know of that selectively inhibits while sparing the COX2 pathway. u can buy for under $10 to potentiate PGF2a release.
'Exposure to the bee venom peptide melittin, to increase PLA(2) substrate availability, potentiated arachidonic acid release'
'Melittin stimulates ... hydrolysis of phospholipids by phospholipase A2 to release arachidonic acid (AA).'
'melittin stimulates the synthesis of PGF-2 alpha and PGI-2 (measured as 6-keto-PGF-1 alpha) in guinea-pig uterus by mechanisms which are calcium dependent.'
In google books search for 'Mechanisms of Physical and Emotional Stress' and pg 94 will summarise most of this.
Anyone tried this sup on their Arachidonic acid cycle to release more PGs? looks pretty interesting
(U can see the studies by searching for the quotes)