Anabolic Pump Question

[Savageous]

Sorry: As I know this is probably the most often used title for a thread in this sub-forum!! Either way.....

I was taking a look through the manual and read the directions for hardgainers. That said, I've read countless other things about Anabolic Pump. I seem to remember that taking AP after a meal is sort of a no-go because it dramatically magnifies the insulin spike. If that were the case, wouldn't that be a good thing for hardgainers?

Any help? Thanks!

 

[bolt10]

idk about magnifying the insulin spike....but you shouldn't be taking AP after a meal because you are trying to use it to activate glut-4 prior to ingesting your carbs..that way they are used efficiently..after a meal would not seem good in my opinion

 

[Savageous]

idk about magnifying the insulin spike....but you shouldn't be taking AP after a meal because you are trying to use it to activate glut-4 prior to ingesting your carbs..that way they are used efficiently..after a meal would not seem good in my opinion

I'm pretty sure I remember Jacob making a point of that at one time or another - the magnifying the insulin spike thing. Otherwise, I'm sure the AP will still activate glut-4 as that is what AP does. What say you?

 

[Mulletsoldier]

Taking Anabolic Pump after a meal is a no-go because the Insulin spike itself negates the purpose of taking AP. GLUT4 is an Insulin-reactive isoform. It is not only translocated in the presence of Insulin, but its recession back into the vesicle of the cell is dependent on Insulin as well. It's not that it has a negative effect, but that it will have no effect after a meal is already consumed.

This is why the simple carb instructions were given for hard-gainers. To utilize the speed of their metabolism and the natural partitioning effect of Insulin in an environment very conducive to its presence.

 

[Savageous]

Taking Anabolic Pump after a meal is a no-go because the Insulin spike itself negates the purpose of taking AP. GLUT4 is an Insulin-reactive isoform. It is not only translocated in the presence of Insulin, but its recession back into the vesicle of the cell is dependent on Insulin as well. It's not that it has a negative effect, but that it will have no effect after a meal is already consumed.

This is why the simple carb instructions were given for hard-gainers. To utilize the speed of their metabolism and the natural partitioning effect of Insulin in an environment very conducive to its presence.

Good answer. I'm shy of a precise understanding, though. AP brings GLUT-4 about without utilizing insulin. Then, when insulin is present, GLUT-4 does all of the carb sucking before returning to the vesicle of the cell because of the presence of insulin. Is that right? If that is the case, what happens if you take AP and then ingest nothing? Does GLUT-4 surface and then remain until you do ingest something with carbs? Thanks, man!

 

[Mulletsoldier]

Good answer. I'm shy of a precise understanding, though. AP brings GLUT-4 about without utilizing insulin. Then, when insulin is present, GLUT-4 does all of the carb sucking before returning to the vesicle of the cell because of the presence of insulin. Is that right? If that is the case, what happens if you take AP and then ingest nothing? Does GLUT-4 surface and then remain until you do ingest something with carbs? Thanks, man!

Carbs are eaten --> blood glucose rises --> pancreatic Insulin release occurs --> Insulin reactive protein cascades activate GLUT4 translocation --> GLUT4 creates a glucose-permeable plasma membrane for a finite period --> GLUT4 recedes in a somewhat corollary manner with Insulin.

(that was grossly, grossly, grossly oversimplified for the purposes of clarity)

The beauty of Anabolic Pump is that it mediates an Insulin-reactive process independent of Insulin. However, it cannot alter every facet of this relationship. One of these facets is that GLUT4 does not recede until Insulin has receded as well.

If you were to eat AP it would activate these Insulin-reactive protein cascades for a time period unique to each individual's body chemistry.

 

[Guest]

I'm pretty sure I remember Jacob making a point of that at one time or another - the magnifying the insulin spike thing. Otherwise, I'm sure the AP will still activate glut-4 as that is what AP does. What say you?

You have a point, and I been thinking about this recently. When AP and P-slin are taken 15 minutes before a meal. We are activating GLUT4 in the absence of Insulin.

Less insulin is needed and glucose is directed to muscle cells.

Would be an interesting experiement to eat a bigger meal and take AP 15 minutes after you eat. With Circulating Insulin and AP, you could have a huge synergy but of course, the down side is your risk fat gain. If you are a hard gainer, you probably do not gain fat other wise.

You could even dose 1 Pslin/1AP 15 minutes after a meal but be sure to eat a ****load of carbohydrates!

 

[Savageous]

Carbs are eaten --> blood glucose rises --> pancreatic Insulin release occurs --> Insulin reactive protein cascades activate GLUT4 translocation --> GLUT4 creates a glucose-permeable plasma membrane for a finite period --> GLUT4 recedes in a somewhat corollary manner with Insulin.

(that was grossly, grossly, grossly oversimplified for the purposes of clarity)

The beauty of Anabolic Pump is that it mediates an Insulin-reactive process independent of Insulin. However, it cannot alter every facet of this relationship. One of these facets is that GLUT4 does not recede until Insulin has receded as well.

If you were to eat AP it would activate these Insulin-reactive protein cascades for a time period unique to each individual's body chemistry.

Incredible! Thanks for that. I understand the gross (x3) oversimplifaction for its purpose. You are, indeed, the man!

 

[Savageous]

You have a point, and I been thinking about this recently. When AP and P-slin are taken 15 minutes before a meal. We are activating GLUT4 in the absence of Insulin.

Less insulin is needed and glucose is directed to muscle cells.

Would be an interesting experiement to eat a bigger meal and take AP 15 minutes after you eat. With Circulating Insulin and AP, you could have a huge synergy but of course, the down side is your risk fat gain. If you are a hard gainer, you probably do not gain fat other wise.

You could even dose 1 Pslin/1AP 15 minutes after a meal but be sure to eat a ****load of carbohydrates!

I've been thinking of trying that idea as well. Which is why I asked about it. Thanks for taking the time to peek at my question!

 

[Wolfenstein]

I've been thinking of trying that idea as well. Which is why I asked about it. Thanks for taking the time to peek at my question!

I was considering this product, but it has too much anti-inflammatory properties for bulking, I cant see this increasing mass like it states?:blink:

 

[Guest]

I was considering this product, but it has too much anti-inflammatory properties for bulking, I cant see this increasing mass like it states?:blink:

Are you serious? You must be thinking about another product or been miss-informed.

Almost like stating Insulin is useless for bulking.

I would hate to use a supplement that super saturates muscle cells with glycogen(which in turn deposits more circulating Amino Acids); increases muscular cellular hydration (which is turn creates an very anabolic enviroment at the cellular level);

 

[Wolfenstein]

Are you serious? You must be thinking about another product or been miss-informed.

Almost like stating Insulin is useless for bulking.

I would hate to use a supplement that super saturates muscle cells with glycogen(which in turn deposits more circulating Amino Acids); increases muscular cellular hydration (which is turn creates an very anabolic enviroment at the cellular level);

Why the use of phellodendron? its no better than asprin? and I can just go buy Lagerstroemia for like a 1/8th of the price?:bow28:

 

[Mulletsoldier]

Why the use of phellodendron? its no better than asprin? and I can just go buy Lagerstroemia for like a 1/8th of the price?:bow28:

I think you need to do some more research friend.

You could by Lagerstroemia for 1/8th the price, you could also buy Mucuna P., and any other herb for 1/8th the price, and there is a reason. No herb on the planet is used in its native form. It is broken down into % extracts of certain phyto-chemicals within the plant.

 

[Wolfenstein]

I think you need to do some more research friend.

You could by Lagerstroemia for 1/8th the price, you could also buy Mucuna P., and any other herb for 1/8th the price, and there is a reason. No herb on the planet is used in its native form. It is broken down into % extracts of certain phyto-chemicals within the plant.

Standardized? yeah its still that cheap, and I love the condescending:welcome: , smug tone of all these reps! really turns you on to these company's:rasp:

 

[Guest]

Standardized? yeah its still that cheap, and I love the condescending:welcome: , smug tone of all these reps! really turns you on to these company's:rasp:

LOL.

You approached the thread without an ounce of substance to your claims.

Should we just believe the dude with 20 posts? Maybe but without substance, you represents yourself as a "troll."

 

[Mulletsoldier]

Standardized? yeah its still that cheap, and I love the condescending:welcome: , smug tone of all these reps! really turns you on to these company's:rasp:

Well, when you thought Phell., is only used as an anti-inflammatory, I made an assumption of where your head is at.

 

[Wolfenstein]

LOL.

You approached the thread without an ounce of substance to your claims.

Should we just believe the dude with 20 posts? Maybe but without substance, you represents yourself as a "troll."

Hey look man, you continue to prove my point. Im gonna buy this **** **** either way , it just seems outstanding to me the way some of these people representing businesses talk to clients or possible customers? Maybe im just jealous or in the wrong business:numbered:?

 

[Wolfenstein]

Well, when you thought Phell., is only used as an anti-inflammatory, I made an assumption of where your head is at.

You answered:
me in an professional manner. I didnt mean to direct anything to the mulletman. I know of other eastern medicines(which this company is not original for using) and purposes for phell. including diabetic therapy, I was just generally speaking about its anti muscle synthesizing antiinflammatorys/ just a question.

 

[Mulletsoldier]

You answered:
me in an professional manner. I didnt mean to direct anything to the mulletman. I know of other eastern medicines(which this company is not original for using) and purposes for phell. including diabetic therapy, I was just generally speaking about its anti muscle synthesizing antiinflammatorys/ just a question.

Ah, I see. Yes, Phell., has a myriad of alternative-medicine capabilities including anti-inflammatory, anti-microbial, and obviously the glucose regulative capabilities that we use it for.

This is why I brought up the issue of standardization, however. As you know, it is the phyto., which 'does its work' in a product; and, therein, plants have many different phyto chemicals. Reasoning stands that the overrepresentation of one for a specific purpose means a corollary underrepresentation of others which may have unwanted effects.

 

[Guest]

Hey look man, you continue to prove my point. Im gonna buy this **** **** either way , it just seems outstanding to me the way some of these people representing businesses talk to clients or possible customers? Maybe im just jealous or in the wrong business:numbered:?

What do you do for a living? I like to reverse our roles to prove a point of respect.

 

[Wolfenstein]

What do you do for a living? I like to reverse our roles to prove a point of respect.

Construction.