I was just about to ask a similar question ! 7-oxo DHEA is supposed to have an effect on thyroid hormones, which I’m concerned about, yet I don’t know how much of this product is systemic and would actually do that. Furthermore, DHEA itself does reduce sperm count but I don’t know (and and legitimately concerned) whether 7-oxo-DHEA has a negative effect on sperm production. Hopefully, some of the members here would have more insight regarding this.