timmylong2725
New member
If I am not mistaken, the only available oral 11-oxo's as of late are 11-oxo-androstenedione AKA adrenosterone AKA androst-4-ene-3,11,17-trione.
But, we already know from the work that PA did in the late 90's that delta 4,5 steroids are way more effective orally with two hydroxyls on 3 and 17 instead of 2 ketones - that is why 4-androstenediol replaced androstenedione in the PH arms race to the best testosterone precursor.
Of course, there was also an aromatase component to it as androstenedione is a direct substrate while 4-A-Diol is not.
Since there seems to be no legal trouble that PA or others are getting into selling the oral adrenosterone, why don't they do the logical thing and start selling 11-keto-4-androstenediol AKA adrenosterone with the ketones on 3 and 17 replaced by hydroxyls?
It would almost certainly be a 3-fold (or more) more efficient precursor to 11-KT when swallowed. Just like 1-AD, I'm sure that 11-keto-4-AD is naturally occurring in tiny amounts, so it's not synthetic per-se like M1T or other methylated derivatives.
Maybe they just don't think the extra synthesis work is worth it?
But, we already know from the work that PA did in the late 90's that delta 4,5 steroids are way more effective orally with two hydroxyls on 3 and 17 instead of 2 ketones - that is why 4-androstenediol replaced androstenedione in the PH arms race to the best testosterone precursor.
Of course, there was also an aromatase component to it as androstenedione is a direct substrate while 4-A-Diol is not.
Since there seems to be no legal trouble that PA or others are getting into selling the oral adrenosterone, why don't they do the logical thing and start selling 11-keto-4-androstenediol AKA adrenosterone with the ketones on 3 and 17 replaced by hydroxyls?
It would almost certainly be a 3-fold (or more) more efficient precursor to 11-KT when swallowed. Just like 1-AD, I'm sure that 11-keto-4-AD is naturally occurring in tiny amounts, so it's not synthetic per-se like M1T or other methylated derivatives.
Maybe they just don't think the extra synthesis work is worth it?