5 Amino 1MQ

Cowboy.Spirit

New member
I see Mike has this in a liquid oral version. I know he is well treated on this forum but doesn’t really work orally?

I need 700mg and subq that’s around $2,000.
I’m curious if anyone has used this orally and what result they got from it.
 
5-Amino-1MQ (5-AMQ) is a potent, small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT) with good oral bioavailability, estimated at approximately 38.4% in rat studies. It is known for having high membrane permeability, which makes it suitable for oral administration rather than solely relying on injections.
National Institutes of Health (.gov)
National Institutes of Health (.gov)
+2
Key details regarding 5-amino-1MQ oral bioavailability:
Bioavailability: Studies indicate an oral bioavailability of approximately 38.4% in rats.
Plasma Exposure: The compound displays substantial plasma exposure in rats (mean maximum plasma concentration of 2252 ng/mL).
Elimination Half-life: The oral terminal elimination half-life is around 6.9 hours in rats.
 
Cowboy.Spirit said:
I see Mike has this in a liquid oral version. I know he is well treated on this forum but doesn’t really work orally?

I need 700mg and subq that’s around $2,000.
I’m curious if anyone has used this orally and what result they got from it.
Click to expand...
I don't know about 700 mg but I see most research being done in the 50-150mg range.
 
Ya I have had decent results from the oral only route and have experience with both. Inj is only slightly more effective IME. Definitely hold under the tongue 1min + to enhance absorption. Stack with SLU or cardarine or L-carn or all :) . Keep your dose low and consistent or you will get headaches.
 
HOT TAKE : 5 amino shines in a clean bulk not a cut. It is more of a fat blocker and nutrient partitioner than a true cutter.
 
I found the exact opposite. Did didley squat visibly except when I was already towards the end of a cut. At that point it worked great. I’m sure it’s still working in the background whenever you use it but that’s when I could see that it was working. Also should not cost 2000 for 700mg sub q. There are places that sell the vials cheaper if you look and there are places that make it similar to how you would see an amino blend ( it does hold up in solution).
 
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