I've been using Mike's 1,4 andro for about 4 weeks now. I'm taking 300mg 2x a day. I'm taking this concurrently with One+ so it's difficult to say if my results are from the One+ or 1,4 andro.
I haven't notice increased vascularity or muscle hardness which is supposed to acompany 1,4 andro. I also haven't noticed much of an appetite increase except from what I usually get from the One+.