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  1. BarryScott

    Difference between DHEA vs 1 Testosterone

    What do you mean by "1 testosterone"? To me that means dhb, which is an anabolic steroid, not a prohormone.
  2. BarryScott

    Cardarine affects blood?

    Not necessarily. It could be due to the fact that activation via the "normal" routes (e.g. ampk) that metformin and exercise induces also has other functions that direct activation via ppard agonists doesn't, which counteract the carcinogen effect. Dosage probably does play a role regardless...
  3. BarryScott

    Cardarine affects blood?

    Why? It's only been used in humans for a fraction of those 32 years and we have no idea or even any way of determining if anyone has gotten cancer as a result of cardarine usage. It's irresponsible misinformation.
  4. BarryScott

    Cardarine affects blood?

    Presumably it will have something to do with the fact that exercise and metformin upregulate ppard through ampk enzymes, which is a natural metabolism regulator, whilst ppard agonists like cardarine act on the receptor directly. In any case the evidence that cardarine is carcinogenic is pretty...
  5. BarryScott

    Cardarine affects blood?

    If you look into what ppar-delta receptors do then it makes perfect sense. Certain cancers upregulate ppar-delta (i.e. the same thing cardarine does) and it promotes metastasis of cancer cells. https://pubmed.ncbi.nlm.nih.gov/28097239/
  6. BarryScott

    Cardarine affects blood?

    Plus how long has cardarine really been used by the bodybuilding community now? Like 15 years maybe? Yes, it's been around longer than that but in a laboratory setting - the general public didn't have access to cardarine in the 90's. That's not long enough to see any repercussions of cancer...
  7. BarryScott

    Cardarine affects blood?

    Cardarine is most likely cancerous in humans, that's why gsk stopped developing it. The mechanism by which ppar-delta agonists contribute to cancer is understood now and it's as applicable in humans as it is in rodents. The rodent studies were not flawed, by the way, they did exactly what they...
  8. BarryScott

    Thoughts on GW-0742, aka Super Cardarine’

    Yeah, unfortunately it's never going to be suitable as a mass market drug due to potential carcinogenesis, even if that potential was pretty mild so they dropped all interest in it. It's not just cardarine either, all research in ppar-delta agonists has been dropped pretty much because they've...
  9. BarryScott

    Anyone say the hell with pharma trt and just self ugl trt?

    Most people I know (and myself) just inject half a ml of ugl test a week and call it a day
  10. BarryScott

    Vigorous Steve E-Books

    I downloaded a bottle of his books for free from anonfiles. Pretty meh tbh. Nothing most people don't already know.
  11. BarryScott

    Thoughts on GW-0742, aka Super Cardarine’

    Just going to point out that the whole thing about the rodent studies being flawed isn't correct. It's broscience that got perpetuated by sellers and guys on youtube etc. that don't understand how cancer studies work. 1) The dosage given to rats wasn't as high as people claim. You don't just...
  12. BarryScott

    Self-administered TRT UK - how do I do this? I.e. what, when, where, how etc …

    I'm not sure why you think trt is the answer to this. Seems like what you actually want to do is a normal steroid cycle. What you're proposing is shutting off your own testosterone production to replace it with exogenous testosterone for no reason whatsoever.
  13. BarryScott

    Immortal science brand

    Probably. Their msten definitely did something so I don't see any reason why the epistane would be different. It was a while ago since I used them now though. I buy all my gear from a ugl that has jano test their batches now though. So not really up to date with prohormones and sarms.
  14. BarryScott

    Does anyone think the Liver King is Natty?

    He's absolutely not natty obviously, and is an unscrupulous shill preying on the naive.
  15. BarryScott

    First cycle in years

    I almost always shower immediately after my morning shyte, thankfully.
  16. BarryScott

    First cycle in years

    Reaching forward between my legs allows me to reach my arsehole with toilet paper. Don't think that would work for sticking a pin into my upper glute though.
  17. BarryScott

    First cycle in years

    Like I said, I can't reach them. Don't know why that's so difficult to accept. People have different bone structures and levels of flexibility.
  18. BarryScott

    First cycle in years

    Unfortunately I just cannot reach my glutes, I have tried. My shoulders are pretty beefy, feels like I could go in twice as deep before I got close to bone or anything. I'll maybe try not pushing the before in so far next time and see. Weirdly, the day or so after my pin my skin on the shoulder...
  19. BarryScott

    Immortal science brand

    I used their sister brand "Immortal Strength" msten, and I got shut down and stronger so I'd say g2g
  20. BarryScott

    First cycle in years

    Using 5 a 1" 25g in the shoulders. Can't reach glutes unfortunately.
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