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  1. Arimidex/depression?

    Arimidex lowers estrogen. Estrogen has a positive correlation with both serotonin and cortisol. ALL of these act as stress hormones and have neurotransmitter capacity. You may find that a sudden drop in all three depresses mood while the body readjusts levels to sustain mood. I have had...

  2. Pregnenolone

    "In the above scenario, taking supplemental pregnenolone could contribute to the over-production of cortisol, while a case could be made for supplementing estrogen. Outside the context of pharmaceutical physiology, you'll find that hormonal synthesis doesn't work like the pictures and diagrams...

  3. Pregnenolone

    Hey Godfather I was offered trt here in the UK. I have boxes of Sus 250 just sitting in a cupboard. I figured estrogen was my culprit. I quit flax, fish oil, most grains and followed Ray Peat's diet and supp advices. I am a huge fan of saturated fat - meat, coconut oil, fresh double...

  4. Pregnenolone

    Pregnenolone is the master hormone at the top of the adrenal food chain. It can convert into DHEA or progesterone. DHEA can convert to test or E, progesterone to cortisol. Check out Ray Peat's article on Pregnenolone and DHEA. Some amazing info on there. I use this stuff to shield from...

  5. Trouble sleeping on trt

    I know this is an old post, but something worth mentioning. If you have low thyroid then you can have low T. If your metabolic rate is slower, then hormone production is slower. Even when labs show you are in range for TSH, T4 and T3 that doesn't mean there is not a thyroid problem. Just...

  6. Sky high fsh, lh, normal prolactin & estradiol

    Results in last week: fsh 30.7 u/l lh 9.9 u/l progesterone 7.4 nmol/l oestradiol 92 pmol/l prolactin 225 mu/l Cortisol 600 Doc forgot to ask for test but last time it was in the mid norm range. Various symptoms - insomnia, major fat loss, weird chest pains and anxiety . Initially taking...

  7. Mirtazapine - anabolic/androgenic...?

    Some results! Hey Anabolic and Dr D. Sorry for the delay in responding. I decided to get some bloods done. It turns out Remeron is used (for some reason?) as a therapy for post menopausal women when estrogen is not appropriate, and for hot flushes in women cancer patients. RESULTS: My fsh...

  8. Mirtazapine - anabolic/androgenic...?

    D that is amazing you should mention the memory thing! Yes, it's been happening. Today it was some old school day. I could actually feel the memory, like it was happening again - the Police' Message In A Bottle was playing, I was on the street waiting for a bus. Just a random but...

  9. Mirtazapine - anabolic/androgenic...?

    Just looking at some good controlled studies on SSRI's like Citalopram. They raise cortisol levels. There's also an instant and non diminishing release of oxytocin which may 'trick' the user into believing their serotonin is rising from day one when in fact they are feeling the comfort of a...

  10. Mirtazapine - anabolic/androgenic...?

    Hi Anabolic. Believe me, I know what you mean about docs handing out ssri's like candy. If they had measured my cortisol at the start, it could have saved me nearly 12 months of despair. I asked for the test, but only got it when I got a good doc who I will now stick with. High cortisol...

  11. Mirtazapine - anabolic/androgenic...?

    Hi D, I'm back on it today after a week's break. I have reduced my morning DHEA dose from 150 to 75mg at 0900. The next dose is 75 at 1500. I slept right through last night. Can't remember falling asleep. Was slightly dazed and heavy on waking but when the dhea kicked in 30 mins later...

  12. Mirtazapine - anabolic/androgenic...?

    Anabolicaholic - yes it is bizarre. Think about it. In 2005, 10% of Americans were using anti-depressants. That's 27M people. More than 80% of those got their scrip from a doctor, not a psych, suggesting a short consultation and trial/error protocol. What percentage of those 27M do you...

  13. Mirtazapine - anabolic/androgenic...?

    Not quite mate. I work in construction as a fitter - floors and walls. I'm ex British infantry, and served two tours attached to your US Core Of Engineers as recon and force security in Iraq - 03 and 04, various PMC gigs after that. I've actually walked away from people socially when they've...

  14. Mirtazapine - anabolic/androgenic...?

    Hi Bigflex. I think the reason they switched rather than ditched, is that tapering seems to be a major issue for many. As Dan Kalish asserts, long term use of SSRI's is actually counterproductive by ultimately lowering the amount of neurotransmitters available to perform adequate function...

  15. Mirtazapine - anabolic/androgenic...?

    JD I tried the other ssri's and they worked against my athletic goals. For a start, the dominance of serotonin over dopamine led me to a blunted state of mind - I didn't exactly feel unhappy but there was a lack of drive and desire. I tested this with cycles of tryptophan alone at 4 g per day...

  16. Mirtazapine - anabolic/androgenic...?

    With just a cursory look at the forums covering the use of anti-depressants it appears there are scores of reports that SSRI users switched to mirtazapine and saw a dramatic return to normal levels of sex drive from a previously near non existent state - this includes both sexes. It would...

  17. Mirtazapine - anabolic/androgenic...?

    Mirtazapine is a tetracyclic antidepressant and differs substantially in it's methods of improving mood compared to SSRI's like Prozac. In particular it promotes dopamine and noradrenaline activity, with some serotonin promotion also. Unlike SSRI'S (which curve much more in favour of...

  18. Mirtazapine - anabolic/androgenic...?

    Hi guysNew to this forum but always pop in for a read. The Dr threads are great.i believe the trycyclic anti depressant Mirtazapine to be a growth agent. For the last year I suffered anxiety/mild depression and insomnia and gastro issues after a prolonged phase of working 14 hr days in...
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