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  1. Melatonin supplementation = pineal gland shutdown?

    I take it "CR" is a slow-release melatonin brand? What do you mean by "pharmaceutical drug"? A superior grade of melatonin? Melatonin is melatonin, only the dosage varies between brands. Despite my tone I'm open to all arguments and studies, they just seem to go in the complete opposite...

  2. Melatonin supplementation = pineal gland shutdown?

    What you are stating is false: the majority of studies show best effects for a restful sleep with no morning grogginess 300mcg. Which makes sense as the natural nocturnal production is around 100mcg. Taking 10 times the dose altered slow wave sleep for the worse

  3. The Official OL UK Ghar1ne Q&A

    Pop some and tell us what you feel

  4. Melatonin supplementation = pineal gland shutdown?

    I'm 28. I have closely linked melatonin with my loss of libido as I did bouts of experiments for one week where quitting melatonin restored libido. Also, has anyone noticed a decrease in muscle mass over prolonged melatonin use? I know it's couter-intuitive as it is a somatostatin inhibitor...

  5. Melatonin supplementation = pineal gland shutdown?

    I've been taking Melatonin @500mcg everyday for the past year, and I mean every night before bed without exception. It all started after a long plane trip, I found I slept incredibly better when on it. However what I noticed while on it is that my daytime energy and libido have fallen...

  6. Healing gut after antibiotics

    Thanks a ton for the replies guys, going to give a shot to these

  7. Healing gut after antibiotics

    After several courses of Azythromycin and other Tetracyclines for the past 2 years, my gut has taken a serious toll. It has allowed for candida overgrowth and bad bacteria proliferation. I had a stool test confirm this. I have always been a regular probiotic user and I recently upped my game...

  8. CJC 1295 DAC / MK 677 13 weeks & more!!

    REM sleep (dream stage) is good and necessary, but can't make up for your whole night. You need to hit deep sleep phase for trully healing sleep, and **** all happens during that phase, no moving, no dreaming, NADA! If you're constantly dreaming you may want to cut: Caffeine Nootropics...

  9. CJC 1295 DAC / MK 677 13 weeks & more!!

    That's because it's ****ing up with your sleep not making it better. A true deep sleep makes you rested enough after 6hours so that you'll be jumping out of bed in a second. The fact that you're dreaming so much actually means that you're rarely hitting phase 4 deep sleep. Which happens to me...

  10. Melatonin & androgen receptors

    Sane isn't subjective, sane is what most perfectly mimicks nature's patterns. As we produce around 100mcg melatonin at night, a dose as close as possible to that value is considered sane.

  11. Melatonin & androgen receptors

    And you are more than welcome to do so, without necessarily closing the door to anecdotal reports from this board.

  12. Melatonin & androgen receptors

    I will take individual reports from those willing to report this finding anyways, if you allow me ;-)

  13. Melatonin & androgen receptors

    It looks like there is no definitive study on this particular point in healthy individuals, so I'll take the chance to ask this to individuals on here: Has anyone, taking melatonin regularly in sane amounts ie <1mg at bedtime, experienced a decrease in muscle mass over time as well as a libido...

  14. Mk667- The No BS Straight Scoop ....

    But on the other side that means you'd have to trade sleep for energy, are you sure you'd be willing to?

  15. Mk667- The No BS Straight Scoop ....

    I will! I reserve those experiments for Fridays, in case it messes with my sleep I have two days to recover

  16. Mk667- The No BS Straight Scoop ....

    F*** all bro! I take melatonin on a daily basis so my sleep is usually perfect and when I added the MK all I did was having an 8h semi-awaken dream and waking up with the puffiest eyes ever, unable to do jack **** for the rest of the day haha Seems like it prevents me from reaching the deep...

  17. Mk667- The No BS Straight Scoop ....

    I tried a 10mg dose yesterday morning in the hope it would be low enough for me to sleep. It f***** up my sleep big time again. Is that thing supposed to make you restless?

  18. Melatonin & androgen receptors

    I agree that it's made a tremendous difference in my quality of life, especially when I don't go over 500mcg. Natural nocturnal production is anywhere between 80-120mcg, so it's already a lot. Have you tried the time-release melatonin? How would you compare it to the instant delivery one?

  19. Melatonin & androgen receptors

    We are not talking T levels here, but whether its binding to androgen receptors is affected by Melatonin intake. You could have 1200ng/dl levels and poor receptor activity, making you less of a male than a guy with 500ng/dl and proper androgen receptors activity. Asian males are one example of that

  20. Melatonin & androgen receptors

    Not sure whether I'm correctly understanding the conclusions of this study: Invalid Link Removed Is it to say that Melatonin supplementation downregulates androgen receptors and that would affect testosterone binding and expression? Or is it just a short and local activity that has no...
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