Tiftan090
New member
More than once I've seen it stated that test gets 5alpha reduced on its way through the skin, and this accounts for the greater androgenicity of transdermal test when applied to the scrotum... If you make a transdermal out of prop instead of base, would the ester get cleaved on the way through the skin, or would the ester last until it got into your blood? Can it even interact with 5ar with an ester on it?